ArticleBMC developmental biology2013
An ancient process in a modern mollusc: early development of the shell in Lymnaea stagnalis.
Article in BMC developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Review
- Proteomic analyses reveal the key role of gene co-option in the evolution of the scaly-foot snail scleritome.Communications biology · 2025Article
- The genome of the simultaneously hermaphroditic snail Lymnaea stagnalis reveals an evolutionary expansion of FMRFamide-like receptors.Scientific reports · 2024Article
- The adult shell matrix protein repertoire of the marine snail Crepidula is dominated by conserved genes that are also expressed in larvae.BMC ecology and evolution · 2024Article
- Cell type and gene regulatory network approaches in the evolution of spiralian biomineralisation.Briefings in functional genomics · 2023Review
- Article
- Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages.Royal Society open science · 2022Article
- Brachiopod and mollusc biomineralisation is a conserved process that was lost in the phoronid-bryozoan stem lineage.EvoDevo · 2022Article
- Heme-Peroxidase 2 Modulated by POU2F1 and SOX5 is Involved in Pigmentation in Pacific Oyster (Crassostrea gigas).Marine biotechnology (New York, N.Y.) · 2022Article
- Nonmuscle Myosin II is Required for Larval Shell Formation in a Patellogastropod.Frontiers in cell and developmental biology · 2022Article
- Hydrophilic Shell Matrix Proteins ofGenes · 2021Article
- Mantle Modularity Underlies the Plasticity of the Molluscan Shell: Supporting Data FromFrontiers in genetics · 2021Article
- The pond snail Lymnaea stagnalis.EvoDevo · 2020Review
- Early shell field morphogenesis of a patellogastropod mollusk predominantly relies on cell movement and F-actin dynamics.BMC developmental biology · 2020Article
- The unlimited potential of the great pond snail,eLife · 2020Article
- Computationally predicted gene regulatory networks in molluscan biomineralization identify extracellular matrix production and ion transportation pathways.Bioinformatics (Oxford, England) · 2020Article
- Growth and morphogenesis of the gastropod shell.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Insights into the Evolution of Shells and Love Darts of Land Snails Revealed from Their Matrix Proteins.Genome biology and evolution · 2019Article
- Article
- Novel Genes, Ancient Genes, and Gene Co-Option Contributed to the Genetic Basis of the Radula, a Molluscan Innovation.Molecular biology and evolution · 2018Article
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe morphological variety displayed by the molluscan shell underlies much of the evolutionary success of this phylum. However, the broad diversity of shell forms, sizes, ornamentations and functions contrasts with a deep conservation of early cell movements associated with the initiation of shell construction. This process begins during early embryogenesis with a thickening of an ectodermal, 'dorsal' (opposite the blastopore) population of cells, which then invaginates into the blastocoel to form the shell gland. The shell gland evaginates to form the shell field, which then expands and further differentiates to eventually become the adult shell-secreting organ commonly known as the mantle. Despite the deep conservation of the early shell forming developmental program across molluscan classes, little is known about the fine-scale cellular or molecular processes that underlie molluscan shell development.
resultsUsing modern imaging techniques we provide here a description of the morphogenesis of a gastropod shell gland and shell field using the pulmonate gastropod Lymnaea stagnalis as a model. We find supporting evidence for a hypothesis of molluscan shell gland specification proposed over 60 years ago, and present histochemical assays that can be used to identify a variety of larval shell stages and distinct cell populations in whole mounts.
conclusionsBy providing a detailed spatial and temporal map of cell movements and differentiation events during early shell development in L. stagnalis we have established a platform for future work aimed at elucidation of the molecular mechanisms and regulatory networks that underlie the evo-devo of the molluscan shell.
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