ArticleInternational journal of clinical and experimental medicine2013
Melissa officinalis and Passiflora caerulea infusion as physiological stress decreaser.
Article in International journal of clinical and experimental medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- The effects of melissa officinalis on depression and anxiety in type 2 diabetes patients with depression: a randomized double-blinded placebo-controlled clinical trial.BMC complementary medicine and therapies · 2023Trial
- Effects of DietaryLife (Basel, Switzerland) · 2026Article
- Medicinal Plants for Major Depressive Disorder.Brain sciences · 2026Review
- Bioactive Compounds, Medicinal Benefits, and Contemporary Extraction Methods for Lemon Balm (Food science & nutrition · 2025Review
- Metabolomics provides novel understanding of Melissa officinalis mechanism of action ensuring its calming effect on dogs.BMC veterinary research · 2025Article
- The possible "calming effect" of subchronic supplementation of a standardised phospholipid carrier-basedFrontiers in pharmacology · 2023Article
- The complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2021Article
- The Confrontation between Ethnopharmacology and Pharmacological Tests of Medicinal Plants Associated with Mental and Neurological Disorders.Evidence-based complementary and alternative medicine : eCAM · 2018Review
- Article
- Effect of Melissa officinalis Capsule on the Intensity of Premenstrual Syndrome Symptoms in High School Girl Students.Nursing and midwifery studies · 2015Article
- Protective effect ofAnnals of gastroenterologyArticle
- Anti-anxiety and hypnotic effects of ethanolic and aqueous extracts ofAvicenna journal of phytomedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to determine the effect of a Melissa officinalis and Passiflora caerulea infusion on the severity of physiological chronic stress induced by movement restriction in CF-1 mice. 40 CF-1 male mice, six weeks of age, were divided into 4 groups (n = 10 for each group): (1) Group RS/MP received two treatments, induced stress through movement restriction and a infusion of Melissa officinalis and Passiflora caerulea in a dose of 200 mg/kg, (2) RS group with induced stress using movement restriction, (3) MP group, which received only a infusion, and (4) a CONTROL group that received no treatment. The severity of the stress was obtained by analysis of the physical parameters of body weight, thymus and spleen, and associated biomarkers with stress, corticosterone, and glucose. Animals that consumed Melissa officinalis and Passiflora caerulea infusion had lower plasma corticosterone levels (Student's t test, Welch, p = 0.05), which is the most important biomarker associated with physiological stress, demonstrating a phytotherapy effect.
Indexed as
Identifiers
23844268PMC3703115W1504067469What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.