Trial reportPloS one2013
Functional anatomy of writing with the dominant hand.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- The effects of gross motor exercises on perception and praxis in children with motor coordination difficulties-randomized controlled study.Frontiers in neurology · 2026Trial
- Neural correlates underlying micrographia in Parkinson's disease.Brain : a journal of neurology · 2016Trial
- Neural and motor mechanisms of handwriting: from healthy aging to neurodegenerative disorders.Frontiers in aging neuroscience · 2026Review
- Brain activity and the production of written text during mediumistic trance: A controlled EEG study.PloS one · 2026Article
- Writing the Future: Artificial Intelligence, Handwriting, and Early Biomarkers for Parkinson's Disease Diagnosis and Monitoring.Biomedicines · 2025Review
- The lateralized cerebellum: insights into motor, cognitive, and affective functioning across ages: a scoping review.Journal of neurology · 2025Article
- Differential induction of Parieto-motor plasticity in writer's cramp and cervical dystonia.Neurobiology of disease · 2024Article
- Clinical Implications of Dystonia as a Neural Network Disorder.Advances in neurobiology · 2023Review
- Investigation of the posterior parietal cortex to ventral premotor connection in writer's cramp using transcranial magnetic stimulation.Experimental brain research · 2022Article
- Neural Correlates of Executed Compared to Imagined Writing and Drawing Movements: A Functional Magnetic Resonance Imaging Study.Frontiers in human neuroscience · 2022Article
- A connectivity model of the anatomic substrates underlying Gerstmann syndrome.Brain communications · 2022Article
- Task-specific interhemispheric hypoconnectivity in writer's cramp - An EEG study.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020Article
- The Task at Hand: Fatigue-Associated Changes in Cortical Excitability during Writing.Brain sciences · 2019Article
- Fourth finger dependence of high-functioning autism spectrum disorder in multi-digit force coordination.Scientific reports · 2019Article
- Teaching of cursive writing in the first year of primary school: Effect on reading and writing skills.PloS one · 2019Article
- Altered effective connectivity contributes to micrographia in patients with Parkinson's disease and freezing of gait.Journal of neurology · 2018Article
- Neuroimaging Applications in Dystonia.International review of neurobiology · 2018Review
- Training for Micrographia Alters Neural Connectivity in Parkinson's Disease.Frontiers in neuroscience · 2018Article
- The direct basal ganglia pathway is hyperfunctional in focal dystonia.Brain : a journal of neurology · 2017Article
- Altered brain network measures in patients with primary writing tremor.Neuroradiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
While writing performed by any body part is similar in style, indicating a common program, writing with the dominant hand is particularly skilled. We hypothesized that this skill utilizes a special motor network supplementing the motor equivalence areas. Using functional magnetic resonance imaging in 13 normal subjects, we studied nine conditions: writing, zigzagging and tapping, each with the right hand, left hand and right foot. We identified brain regions activated with the right (dominant) hand writing task, exceeding the activation common to right-hand use and the writing program, both identified without right-hand writing itself. Right-hand writing significantly differed from the other tasks. First, we observed stronger activations in the left dorsal prefrontal cortex, left intraparietal sulcus and right cerebellum. Second, the left anterior putamen was required to initiate all the tested tasks, but only showed sustained activation during the right-hand writing condition. Lastly, an exploratory analysis showed clusters in the left ventral premotor cortex and inferior and superior parietal cortices were only significantly active for right-hand writing. The increased activation with right-hand writing cannot be ascribed to increased effort, since this is a well-practiced task much easier to perform than some of the other tasks studied. Because parietal-premotor connections code for particular skills, it would seem that the parietal and premotor regions, together with basal ganglia-sustained activation likely underlie the special skill of handwriting with the dominant hand.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.