ArticlePloS one2013
Targeted enrichment: maximizing orthologous gene comparisons across deep evolutionary time.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Probe Capture Enrichment Sequencing of amoA Genes Improves the Detection of Diverse Ammonia-Oxidising Archaeal and Bacterial Populations.Molecular ecology resources · 2025Article
- A dense linkage map for a large repetitive genome: discovery of the sex-determining region in hybridizing fire-bellied toads (Bombina bombina and Bombina variegata).G3 (Bethesda, Md.) · 2021Article
- Sequence capture using AFLP-generated baits: A cost-effective method for high-throughput phylogenetic and phylogeographic analysis.Ecology and evolution · 2019Article
- Gene markers for exon capture and phylogenomics in ray-finned fishes.Ecology and evolution · 2019Article
- Towards population genomics in non-model species with large genomes: a case study of the marine zooplanktonRoyal Society open science · 2019Article
- Long-read sequence capture of the haemoglobin gene clusters across codfish species.Molecular ecology resources · 2019Article
- A Guide to Carrying Out a Phylogenomic Target Sequence Capture Project.Frontiers in genetics · 2019Review
- Assexon: Assembling Exon Using Gene Capture Data.Evolutionary bioinformatics online · 2019Article
- Plant phylogenomics based on genome-partitioning strategies: Progress and prospects.Plant diversity · 2018Review
- Hybridization capture reveals microbial diversity missed using current profiling methods.Microbiome · 2018Article
- Multilocus DNA barcoding - Species Identification with Multilocus Data.Scientific reports · 2017Article
- Phylogenomic Insights into Mouse Evolution Using a Pseudoreference Approach.Genome biology and evolution · 2017Article
- Sequence capture by hybridization to explore modern and ancient genomic diversity in model and nonmodel organisms.Nucleic acids research · 2016Review
- Harnessing the power of RADseq for ecological and evolutionary genomics.Nature reviews. Genetics · 2016Review
- An Exon-Capture System for the Entire Class Ophiuroidea.Molecular biology and evolution · 2016Article
- Targeted capture in evolutionary and ecological genomics.Molecular ecology · 2016Review
- Are 100 enough? Inferring acanthomorph teleost phylogeny using Anchored Hybrid Enrichment.BMC evolutionary biology · 2015Article
- Article
- The bee tree of life: a supermatrix approach to apoid phylogeny and biogeography.BMC evolutionary biology · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Estimated phylogenies of evolutionarily diverse taxa will be well supported and more likely to be historically accurate when the analysis contains large amounts of data-many genes sequenced across many taxa. Inferring such phylogenies for non-model organisms is challenging given limited resources for whole-genome sequencing. We take advantage of genomic data from a single species to test the limits of hybridization-based enrichment of hundreds of exons across frog species that diverged up to 250 million years ago. Enrichment success for a given species depends greatly on the divergence time between it and the reference species, and the resulting alignment contains a significant proportion of missing data. However, our alignment generates a well-supported phylogeny of frogs, suggesting that this technique is a practical solution towards resolving relationships across deep evolutionary time.
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