Evidence map›Paper›PMID 23843716›Full record

ArticleClinical medicine insights. Case reports2013

A Fatal Case of Relapsing Pneumonia Caused by Legionella pneumophila in a Patient with Rheumatoid Arthritis After Two Injections of Adalimumab.

Masatoshi Hayashi, Hiroshi Kuraishi, Takeshi Masubuchi, Kaneyuki Furihata, Yuka Aida, Tomonori Kobayakawa, Masao Deguchi, Toshihisa Kojima, Naoki Ishiguro, Toshihisa Kanamono

Abstract readCase Reports
In one paragraph

Article in Clinical medicine insights. Case reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pulmonary Sarcoidosis in Behçet's Disease Treated with Adalimumab.European journal of case reports in internal medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Masatoshi HayashiDepartment of Orthopedics Surgery and Rheumatology, Nagano Red Cross Hospital, Wakasato, Nagano, Japan.
Hiroshi Kuraishi
Takeshi Masubuchi
Kaneyuki Furihata
Yuka Aida
Tomonori Kobayakawa
Masao Deguchi
Toshihisa Kojima
Naoki Ishiguro
Toshihisa Kanamono

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a rare fatal case of relapsing pneumonia caused by Legionella pneumophila in a patient with rheumatoid arthritis after only two injections of adalimumab. A 78-year-old Japanese woman with a 14-year history of rheumatoid arthritis was prescribed adalimumab because her disease activity remained high. However, 8 days after her second injection of adalimumab, she was admitted to our hospital and diagnosed with pneumonia caused by L. pneumophila. Following intravenous antibiotic therapy, she recovered completely from pneumonia and was discharged on day 10, but pneumonia relapsed, resulting in death 79 days after the first episode of pneumonia. L. pneumophila can lead to recurrence of pneumonia that can ultimately prove fatal, similar to the present case. A review of the pertinent literature is also presented.

Indexed as

adalimumabfatal infectionLegionella pneumophilarheumatoid arthritis

Identifiers

PMID23843716
PMCPMC3700963

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.