Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2013
Amodal processing in human prefrontal cortex.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Neural Architecture of Familiar Person Perception: Contributions of Unimodal and Multimodal Brain Regions.Human brain mapping · 2026Article
- What, if anything, can be considered an amodal sensory dimension?Psychonomic bulletin & review · 2024Review
- Flexible encoding of multiple task dimensions in human cerebral cortex.Frontiers in cognition · 2024Article
- Application of the International Classification of Cognitive Disorders in Epilepsy (IC-CoDE) to frontal lobe epilepsy using multicenter data.Epilepsy & behavior : E&B · 2023Article
- The Involvement of the Multiple Demand and Default Mode Networks in a Trial-by-Trial Cognitive Control.Brain sciences · 2023Article
- Cognitive phenotypes in frontal lobe epilepsy.Epilepsia · 2022Article
- Extended Frontal Networks for Visual and Auditory Working Memory.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Novel Cognitive Functions Arise at the Convergence of Macroscale Gradients.Journal of cognitive neuroscience · 2022Review
- On the relationship between maps and domains in inferotemporal cortex.Nature reviews. Neuroscience · 2021Review
- Structure, function and connectivity fingerprints of the frontal eye field versus the inferior frontal junction: A comprehensive comparison.The European journal of neuroscience · 2021Review
- Cross-Modal Transfer Following Auditory Task-Switching Training in Old Adults.Frontiers in psychology · 2021Article
- Disrupted modulation of thalamus activation and thalamocortical connectivity during dual task performance in schizophrenia.Schizophrenia research · 2019Article
- Cross-modal transfer after auditory task-switching training.Memory & cognition · 2019Article
- Functional Fractionation of the Cingulo-opercular Network: Alerting Insula and Updating Cingulate.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Switching attention from internal to external information processing: A review of the literature and empirical support of the resource sharing account.Psychonomic bulletin & review · 2019Review
- Functional dissociation of the inferior frontal junction from the dorsal attention network in top-down attentional control.Journal of neurophysiology · 2018Article
- Sensory-biased attention networks in human lateral frontal cortex revealed by intrinsic functional connectivity.NeuroImage · 2017Article
- Sensory-Biased and Multiple-Demand Processing in Human Lateral Frontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Central attention is serial, but midlevel and peripheral attention are parallel-A hypothesis.Attention, perception & psychophysics · 2016Review
- Parsing the Behavioral and Brain Mechanisms of Third-Party Punishment.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
Abstract
Information enters the cortex via modality-specific sensory regions, whereas actions are produced by modality-specific motor regions. Intervening central stages of information processing map sensation to behavior. Humans perform this central processing in a flexible, abstract manner such that sensory information in any modality can lead to response via any motor system. Cognitive theories account for such flexible behavior by positing amodal central information processing (e.g., "central executive," Baddeley and Hitch, 1974; "supervisory attentional system," Norman and Shallice, 1986; "response selection bottleneck," Pashler, 1994). However, the extent to which brain regions embodying central mechanisms of information processing are amodal remains unclear. Here we apply multivariate pattern analysis to functional magnetic resonance imaging (fMRI) data to compare response selection, a cognitive process widely believed to recruit an amodal central resource across sensory and motor modalities. We show that most frontal and parietal cortical areas known to activate across a wide variety of tasks code modality, casting doubt on the notion that these regions embody a central processor devoid of modality representation. Importantly, regions of anterior insula and dorsolateral prefrontal cortex consistently failed to code modality across four experiments. However, these areas code at least one other task dimension, process (instantiated as response selection vs response execution), ensuring that failure to find coding of modality is not driven by insensitivity of multivariate pattern analysis in these regions. We conclude that abstract encoding of information modality is primarily a property of subregions of the prefrontal cortex.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.