ReviewJournal of neurovirology2014
The neuroimmune response to West Nile virus.
Review in Journal of neurovirology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Review
- Interleukin-17A signaling promotes CD8+ T cell cytotoxicity against West Nile virus infection through enhancing PI3K-mTOR-mediated metabolism.PLoS pathogens · 2025Article
- Exposure of negative-sense viral RNA in the cytoplasm initiates innate immunity to West Nile virus.Molecular cell · 2025Article
- Engagement of AKT and ERK signaling pathways facilitates infection of human neuronal cells with West Nile virus.Journal of virus eradication · 2024Article
- Involvement of host microRNAs in flavivirus-induced neuropathology: An update.Journal of biosciences · 2022Review
- Role of Dendritic Cells in Viral Brain Infections.Frontiers in immunology · 2022Review
- Article
- Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross.G3 (Bethesda, Md.) · 2017Article
- A guinea pig model of Zika virus infection.Virology journal · 2017Article
- Identification of host genes leading to West Nile virus encephalitis in mice brain using RNA-seq analysis.Scientific reports · 2016Article
- Everything You Always Wanted to Know About Rabies Virus (But Were Afraid to Ask).Annual review of virology · 2015Review
- Multiplexed digital mRNA profiling of the inflammatory response in the West Nile Swiss Webster mouse model.PLoS neglected tropical diseases · 2014Article
- West nile virus infections in children.Current infectious disease reports · 2014Article
- Integrated analysis of microRNAs and their disease related targets in the brain of mice infected with West Nile virus.Virology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent introduction of highly pathogenic strains of West Nile virus (WNV) into naïve populations in Europe, Israel, and the USA has resulted in a marked increase in both the number of reported cases and the severity of disease compared to previous outbreaks. The impact of the increased virulence of recently emerged strains of WNV is exacerbated by the fact that antiviral therapies and vaccines are not currently available for use in humans. A greater understanding of the viral and host factors involved in WNV-mediated neuropathology is necessary to facilitate the development of novel therapeutic approaches. This review summarizes the current state of knowledge of the role of the cell-intrinsic innate immune responses as well as the cell-mediated innate and adaptive immune responses in promoting the detection and clearance of WNV from the CNS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.