ReviewCalcified tissue international2013
Tools in the assessment of sarcopenia.
Review in Calcified tissue international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03955302 (Ultrasound Assessment of Muscle Architecture Before and After the Implementation of a Physical Exercise Regime in the Water in a Frail Elderly Population), which is not on this map. Cited by 126 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Assessment of Muscle Architecture Before and After the Implementation of a Physical Exercise Regime in the Water in a Frail Elderly Population
Who cites it
126 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Psoas muscle quantified muscle status and long-term mortality after cardiovascular interventions.Annals of medicine · 2023Pooled it
- Calf Circumference and All-Cause Mortality: A Systematic Review and Meta-Analysis Based on Trend Estimation Approaches.The journal of nutrition, health & aging · 2022Pooled it
- Frailty Assessment in Heart Failure: an Overview of the Multi-domain Approach.Current heart failure reports · 2018Pooled it
- Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Pooled it
- Pooled it
- [Impact of osteoporosis on physical performance parameters of middle-aged and elderly individuals-a cross-sectional study].Orthopadie (Heidelberg, Germany) · 2023Trial
- Trial
- Muscle morphology changes over 1-year in patients with rheumatoid arthritis: a prospective cohort study using muscle ultrasound.Advances in rheumatology (London, England) · 2026Observational
- A Practical Anthropometric Model Incorporating Calf Circumference to Estimate Appendicular Lean Mass in Women with Systemic Lupus Erythematosus.Muscles (Basel, Switzerland) · 2026Article
- Development of a sarcopenia identification model for older adults with multimorbidity in Xinjiang communities, Northwest China: a cross-sectional study.BMC geriatrics · 2026Article
- Smartphone video-based knee extension moments during chair rise relate to MRI measures of muscle function.medRxiv : the preprint server for health sciences · 2026Article
- Changes in Bioelectrical Impedance Analysis and Lipid Profile in Children Diagnosed with Short Stature Who Undergo Growth Hormone Therapy: One Single-Center Experience.Medicina (Kaunas, Lithuania) · 2026Article
- Smartphone Video-Based Knee Extension Moments During Chair Rise Relate to MRI Measures of Muscle Force-Generating Capacity.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Prognostic impact of muscle mass in idiopathic interstitial pneumonia: analysis of idiopathic pulmonary fibrosis and other idiopathic interstitial pneumonias.BMC pulmonary medicine · 2025Article
- CT assessment of total abdominal muscle area index (TAMAI) as a predictive tool for early post operative complications in laparoscopic sleeve gastrectomy: a prospective case-control study.BMC gastroenterology · 2025Article
- Arabic Adaptation and Validation of the SARC-F Questionnaire for Sarcopenia Screening in Elderly Populations: Exploration of Associated Factors.Journal of aging research · 2025Article
- Influence of androgen deprivation therapy on physical performance and muscle strength in prostate cancer patients - a systematic review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Review
- Lower creatinine-to-cystatin c ratio associated with increased risk of incident amyotrophic lateral sclerosis in the prospective UK biobank cohort.Scientific reports · 2024Article
- Article
- Navigating the Intersection: Sarcopenia and Sarcopenic Obesity in Inflammatory Bowel Disease.Biomedicines · 2024Review
66 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
This review provides a framework for the development of an operational definition of sarcopenia and of the potential end points that might be adopted in clinical trials among older adults. While the clinical relevance of sarcopenia is widely recognized, there is currently no universally accepted definition of the disorder. The development of interventions to alter the natural history of sarcopenia also requires consensus on the most appropriate end points for determining outcomes of clinical importance which might be utilized in intervention studies. We review current approaches to the definition of sarcopenia and the methods used for the assessment of various aspects of physical function in older people. The potential end points of muscle mass, muscle strength, muscle power, and muscle fatigue, as well as the relationships between them, are explored with reference to the availability and practicality of the available methods for measuring these end points in clinical trials. Based on current evidence, none of the four potential outcomes in question is sufficiently comprehensive to recommend as a uniform single outcome in randomized clinical trials. We propose that sarcopenia may be optimally defined (for the purposes of clinical trial inclusion criteria as well as epidemiological studies) using a combination of measures of muscle mass and physical performance. The choice of outcome measures for clinical trials in sarcopenia is more difficult; co-primary outcomes, tailored to the specific intervention in question, may be the best way forward in this difficult but clinically important area.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.