Evidence map›Paper›PMID 23842132›Full record

ArticleAIDS (London, England)2013

Sexual behaviour in a rural high HIV prevalence South African community: time trends in the antiretroviral treatment era.

Nuala McGrath, Jeffrey W Eaton, Till W Bärnighausen, Frank Tanser, Marie-Louise Newell

Open access · hybridAbstract read
In one paragraph

Article in AIDS (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

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  13. The Art of HIV Elimination: Past and Present Science.Journal of AIDS & clinical research · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Nuala McGrathaAcademic Unit of Primary Care and Population Sciences, and Division of Social Statistics and Demography, University of Southampton, Southampton, UK bAfrica Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, South Africa cDepartment of Infectious Disease Epidemiology, Imperial College London, London, UK dDepartment of Global Health, Harvard School of Public Health, Boston, USA eFaculty of Medicine, University of Southampton, Southampton, UK.
Jeffrey W Eaton
Till W Bärnighausen
Frank Tanser
Marie-Louise Newell
University of Southampton · GBHarvard Global Health Institute · USImperial College London · GB

Funding

Impact of Antiretroviral Therapy on HIV Epidemic DynamicsR01MH083539 · NIMH · BROWN UNIVERSITY · PI LURIE, MARK NATHAN · 2009 to 2012
$2.2M
Understanding causal pathways of HIV acquisition and transmission: a multi-level,R01HD058482 · NICHD · UNIVERSITY OF KWAZULU-NATAL · PI BARNIGHAUSEN, TILL, TANSER, FRANK COURTENEY · 2008 to 2012
$1.2M
NICHD NIH HHS 1R01-HD058482-01NICHD NIH HHS R01 HD058482NIMH NIH HHS 1R01MH083539-01Wellcome Trust 082384Wellcome Trust 082384/Z/07/ZWellcome Trust 083495Wellcome Trust 097410Wellcome Trust WT083495MA
6 · The paper itself

Abstract

objectivesData from generalized epidemic settings have consistently found that patients on antiretroviral therapy (ART) reduce sexual risk behaviours, but how sexual behaviour changes in the general population in response to ART availability, including amongst HIV-uninfected and undiagnosed adults, has not been characterized in these settings.

designGeneral population open cohort.

methodsWe report trends in sexual behaviour indicators for men aged 17-54 years and women aged 17-49 years in rural KwaZulu-Natal province, based on annual sexual behaviour surveys during ART scale-up from 2005 to 2011. Estimates are adjusted for survey nonparticipation and nonresponse to individual survey items using inverse probability weighting and multiple imputation. Trends are presented by HIV status, knowledge of status, age and marital status.

resultsReports of condom use at last sex with a regular partner increased by 2.6% points per year [95% confidence interval (CI) 1.5%, 3.7%] for men and 4.1% per year (3.0%, 5.3%) for women. Condom use at last sex with a casual partner was high and did not change significantly over the period for both sexes. There were statistically significant declines in the percentage reporting multiple partnerships in the last year and the point prevalence of concurrency. Trends within subgroups were generally consistent with overall estimates.

conclusionWe find no evidence of increased sexual risk-taking following ART availability and protective changes in some behaviours, suggesting that general trends in sexual behaviour are not counter-acting preventive effects of HIV treatment. Continued monitoring of population-level sexual behaviour indicators will be essential to interpret the success of combination-prevention programmes.

Indexed as

Risk-TakingAdolescentAdultFemaleHealth Services AccessibilityHIV InfectionsHumansMaleMiddle AgedRural HealthSexual BehaviorSouth AfricaTime FactorsYoung Adult

Identifiers

PMID23842132
PMCPMC3773237
OpenAlexW2035070058

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.