ArticleOrganic letters2013
Ruthenium catalyzed reductive coupling of paraformaldehyde to trifluoromethyl allenes: CF3-bearing all-carbon quaternary centers.
Article in Organic letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Formaldehyde and its surrogates as a C1 platform for defossilised modern societies.Chemical Society reviews · 2025Review
- Three-Component Approach to Densely Functionalized Trifluoromethyl Allenols by Asymmetric Organocatalysis.Journal of the American Chemical Society · 2023Article
- Non-Palladium-Catalyzed Approach to the Synthesis of (Molecules (Basel, Switzerland) · 2022Article
- Copper-catalyzed hydroformylation and hydroxymethylation of styrenes.Chemical science · 2021Article
- Allenes and Dienes as Chiral Allylmetal Pronucleophiles in Catalytic Enantioselective C=X Addition: Historical Perspective and State-of-The-Art Survey.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Inversion of Enantioselectivity in Allene Gas versus Allyl Acetate Reductive Aldehyde Allylation Guided by Metal-Centered Stereogenicity: An Experimental and Computational Study.ACS catalysis · 2019Article
- Cyclometalated Iridium-PhanePhos Complexes Are Active Catalysts in Enantioselective Allene-Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters.Journal of the American Chemical Society · 2019Article
- Intermolecular Metal-Catalyzed Reductive Coupling of Dienes, Allenes, and Enynes with Carbonyl Compounds and Imines.Chemical reviews · 2018Review
- A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes.Journal of the American Chemical Society · 2018Article
- Catalytic Enantioselective Carbonyl Allylation and Propargylation via Alcohol-Mediated Hydrogen Transfer: Merging the Chemistry of Grignard and Sabatier.Accounts of chemical research · 2017Article
- Carbonyl anti-(α-Amino)allylation via Ruthenium Catalyzed Hydrogen Autotransfer: Use of an Acetylenic Pyrrole as an Allylmetal Pronucleophile.Organic letters · 2017Article
- Alkynes as Electrophilic or Nucleophilic Allylmetal Precursors in Transition-Metal Catalysis.Angewandte Chemie (International ed. in English) · 2017Review
- Enantioselective Formation of CFJournal of the American Chemical Society · 2017Article
- Hydroxymethylation beyond Carbonylation: Enantioselective Iridium-Catalyzed Reductive Coupling of Formaldehyde with Allylic Acetates via Enantiotopic π-Facial Discrimination.Journal of the American Chemical Society · 2016Article
- Copper-Catalyzed Borylative Cross-Coupling of Allenes and Imines: Selective Three-Component Assembly of Branched Homoallyl Amines.Angewandte Chemie (International ed. in English) · 2016Article
- Diene hydroaminomethylationChemical science · 2016Article
- Ligand-Controlled Regioselective Copper-Catalyzed Trifluoromethylation To Generate (Trifluoromethyl)allenes.Organic letters · 2015Article
- Ruthenium-catalyzed C-C coupling of fluorinated alcohols with allenes: dehydrogenation at the energetic limit of β-hydride elimination.Angewandte Chemie (International ed. in English) · 2015Article
- Alkyne hydroacylation: switching regioselectivity by tandem ruthenium catalysis.Journal of the American Chemical Society · 2015Article
- Copper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetates.Synthesis · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Trifluoromethyl substituted allenes engage in ruthenium catalyzed reductive couplings with paraformaldehyde to form products of hydrohydroxymethylation as single regioisomers. This method enables generation of CF3-bearing all-carbon quaternary stereocenters.
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Registered trials
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