ArticleBMC plant biology2013
The dual targeting ability of type II NAD(P)H dehydrogenases arose early in land plant evolution.
Article in BMC plant biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Oil body membrane proteins as sensors of salt stress in sunflower seedlings: a proteomic insight.Plant signaling & behavior · 2025Article
- The evolution of strictly monofunctional naphthoquinol C-methyltransferases is vital in cyanobacteria and plastids.The Plant cell · 2023Article
- Mitochondria in photosynthetic cells: Coordinating redox control and energy balance.Plant physiology · 2023Article
- Article
- Genomic comparison of two independent seagrass lineages reveals habitat-driven convergent evolution.Journal of experimental botany · 2018Article
- Alternative Respiratory Pathway Component Genes (AOX and ND) in Rice and Barley and Their Response to Stress.International journal of molecular sciences · 2018Article
- Role of Type 2 NAD(P)H Dehydrogenase NdbC in Redox Regulation of Carbon Allocation inPlant physiology · 2017Article
- A Dedicated Type II NADPH Dehydrogenase Performs the Penultimate Step in the Biosynthesis of Vitamin K1 in Synechocystis and Arabidopsis.The Plant cell · 2015Article
- Chloroplast signaling within, between and beyond cells.Frontiers in plant science · 2015Review
- Suppression of NDA-type alternative mitochondrial NAD(P)H dehydrogenases in arabidopsis thaliana modifies growth and metabolism, but not high light stimulation of mitochondrial electron transport.Plant & cell physiology · 2014Article
- Coordination of plant mitochondrial biogenesis: keeping pace with cellular requirements.Frontiers in plant science · 2014Review
- Dual targeting of peroxisomal proteins.Frontiers in physiology · 2013Review
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType II NAD(PH) dehydrogenases are located on the inner mitochondrial membrane of plants, fungi, protists and some primitive animals. However, recent observations have been made which identify several Arabidopsis type II dehydrogenases as dual targeted proteins. Targeting either mitochondria and peroxisomes or mitochondria and chloroplasts.
resultsMembers of the ND protein family were identified in various plant species. Phylogenetic analyses and subcellular targeting predictions were carried out for all proteins. All ND proteins from three model plant species Arabidopsis, rice and Physcomitrella were cloned as N- and C-terminal GFP fusions and subcellular localisations were determined. Dual targeting of plant type II dehydrogenases was observed to have evolved early in plant evolution and to be widespread throughout different plant species. In all three species tested dual targeting to both mitochondria and peroxisomes was found for at least one NDA and NDB type protein. In addition two NDB type proteins from Physcomitrella were also found to target chloroplasts. The dual targeting of NDC type proteins was found to have evolved later in plant evolution.
conclusionsThe functions of type II dehydrogenases within plant cells will have to be re-evaluated in light of this newly identified subcellular targeting information.
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