ReviewNeural plasticity2013
Is sleep essential for neural plasticity in humans, and how does it affect motor and cognitive recovery?
Review in Neural plasticity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Acupuncture for post-stroke hiccup: an overview of systematic reviews.Frontiers in neurology · 2025Pooled it
- Traditional Chinese Medicine for Post-stroke Sleep Disorders: The Evidence Mapping of Clinical Studies.Frontiers in psychiatry · 2022Pooled it
- Efficacy of Valerian Extract on Sleep Quality after Coronary Artery bypass Graft Surgery: A Triple-Blind Randomized Controlled Trial.Chinese journal of integrative medicine · 2021Trial
- Does sleep matter for recovery after stroke? Functional severity shapes the association between sleep and functional outcome during inpatient stroke rehabilitation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Temporal dynamics and associated factors of sleep quality in Chinese boarding high school students: a repeated cross-sectional study across four waves (2019-2024).Scientific reports · 2026Article
- Neurobiophilia.Brain sciences · 2026Review
- Chronotype in alpha-tACS: Preliminary evidence hints at sleep quality modulation of aftereffects in evening types in the morning.Neurobiology of sleep and circadian rhythms · 2025Article
- Promoting Child Wellness: A Narrative Review of Positive Childhood Experiences.Behavioral sciences (Basel, Switzerland) · 2025Review
- Region-specific non-rapid eye movement delta activity is associated with stroke recovery.Sleep · 2025Article
- EEG Abnormalities and Phenotypic Correlates in Preschoolers with Autism Spectrum Disorder: A Single-Center Study.Journal of clinical medicine · 2025Article
- Martial arts induce quasicritical brain states: a unified, multiscale, and mechanistic theory of brain health optimization.Frontiers in psychology · 2025Article
- Salivary IL-1 Beta Level Associated with Poor Sleep Quality in Children/Adolescents with Autism Spectrum Disorder.Pediatric reports · 2024Article
- The Burden of Sleep/Wake Disorders: Excessive Daytime Sleepiness and Insomnia Project.Methods and protocols · 2024Article
- Disentangling neuroplasticity mechanisms in post-stroke language recovery.Brain and language · 2024Review
- Occupational burnout and chronic fatigue in the work of academic teachers-moderating role of selected health behaviours.PloS one · 2023Article
- Parasomnias and Disruptive Sleep-Related Disorders: Insights from Local Sleep Findings.Journal of clinical medicine · 2022Article
- Sleep and brain evolution across the human lifespan: A mutual embrace.Frontiers in network physiology · 2022Review
- Association between Sleep Disturbances at Subacute Stage of Mild Traumatic Brain Injury and Long-Term Outcomes.Neurotrauma reports · 2022Article
- Sleep-Based Interventions in Alzheimer's Disease: Promising Approaches from Prevention to Treatment along the Disease Trajectory.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Sleep in the Aging Brain.Brain sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a general consensus that sleep is strictly linked to memory, learning, and, in general, to the mechanisms of neural plasticity, and that this link may directly affect recovery processes. In fact, a coherent pattern of empirical findings points to beneficial effect of sleep on learning and plastic processes, and changes in synaptic plasticity during wakefulness induce coherent modifications in EEG slow wave cortical topography during subsequent sleep. However, the specific nature of the relation between sleep and synaptic plasticity is not clear yet. We reported findings in line with two models conflicting with respect to the underlying mechanisms, that is, the "synaptic homeostasis hypothesis" and the "consolidation" hypothesis, and some recent results that may reconcile them. Independently from the specific mechanisms involved, sleep loss is associated with detrimental effects on plastic processes at a molecular and electrophysiological level. Finally, we reviewed growing evidence supporting the notion that plasticity-dependent recovery could be improved managing sleep quality, while monitoring EEG during sleep may help to explain how specific rehabilitative paradigms work. We conclude that a better understanding of the sleep-plasticity link could be crucial from a rehabilitative point of view.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.