ArticleeLife2013
The genome sequence of the colonial chordate, Botryllus schlosseri.
Article in eLife, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
128 citing papers in PubMed, 252 citations in OpenAlex.
- Anatomical and functional organisation of the cholinergic nervous system in the tunicatebioRxiv : the preprint server for biology · 2026Article
- Electrical stimulation promotes longevity and regeneration in a colonial chordate.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Survival Benefits Outweigh Germline Competition Costs in Kin Chimeras.bioRxiv : the preprint server for biology · 2026Article
- Tunicates have a complex, highly dynamic TNF superfamily.PloS one · 2026Article
- Germline stem cell isolation, lineage tracing, and aging in a protochordate.bioRxiv : the preprint server for biology · 2025Article
- A MgBMC genomics · 2025Article
- Electrical Stimulation Rejuvenates Tunicates: Altered Stem Cell and Immune Activity.bioRxiv : the preprint server for biology · 2025Article
- First chromosome-level genome assembly of the colonial chordate model Botryllus schlosseri (Tunicata).GigaScience · 2025Article
- Lung microbiome: new insights into the pathogenesis of respiratory diseases.Signal transduction and targeted therapy · 2024Review
- Lessons on neurodegeneration and aging from the Lagoon of Venice: the marine invertebrateBrain communications · 2024Article
- Salpa genome and developmental transcriptome analyses reveal molecular flexibility enabling reproductive success in a rapidly changing environment.Scientific reports · 2023Article
- Women in tunicate research: Pioneers of the past and their present legacy.Genesis (New York, N.Y. : 2000) · 2023Article
- Stem cell-mediated development, regeneration, chimerism, and aging in the colonial chordate Botryllus schlosseri.Genesis (New York, N.Y. : 2000) · 2023Article
- De novo genome assembly and comparative genomics for the colonial ascidian Botrylloides violaceus.G3 (Bethesda, Md.) · 2023Article
- Multiple Forms of Neural Cell Death in the Cyclical Brain Degeneration of A Colonial Chordate.Cells · 2023Article
- Recent advances in cancer fusion transcript detection.Briefings in bioinformatics · 2023Review
- Contributions from both the brain and the vascular network guide behavior in the colonial tunicate Botryllus schlosseri.The Journal of experimental biology · 2022Article
- Two distinct evolutionary conserved neural degeneration pathways characterized in a colonial chordate.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Metazoans and Intrinsic Apoptosis: An Evolutionary Analysis of the Bcl-2 Family.International journal of molecular sciences · 2022Article
- The Genome of the "Sea Vomit"Life (Basel, Switzerland) · 2021Article
68 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 5 institutions in 3 countries.
Funding
Abstract
Botryllus schlosseri is a colonial urochordate that follows the chordate plan of development following sexual reproduction, but invokes a stem cell-mediated budding program during subsequent rounds of asexual reproduction. As urochordates are considered to be the closest living invertebrate relatives of vertebrates, they are ideal subjects for whole genome sequence analyses. Using a novel method for high-throughput sequencing of eukaryotic genomes, we sequenced and assembled 580 Mbp of the B. schlosseri genome. The genome assembly is comprised of nearly 14,000 intron-containing predicted genes, and 13,500 intron-less predicted genes, 40% of which could be confidently parceled into 13 (of 16 haploid) chromosomes. A comparison of homologous genes between B. schlosseri and other diverse taxonomic groups revealed genomic events underlying the evolution of vertebrates and lymphoid-mediated immunity. The B. schlosseri genome is a community resource for studying alternative modes of reproduction, natural transplantation reactions, and stem cell-mediated regeneration. DOI:http://dx.doi.org/10.7554/eLife.00569.001.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.