ArticlePloS one2013
Molecular evolutionary analysis of the Alfin-like protein family in Arabidopsis lyrata, Arabidopsis thaliana, and Thellungiella halophila.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 49 citations in OpenAlex.
- ALFIN-LIKE H3K4me3 reader proteins regulate embryogenesis inLife science alliance · 2027Article
- Functional characterization ofFrontiers in plant science · 2026Article
- H3K4me3 binding ALFIN-LIKE proteins recruit SWR1 for gene-body deposition of H2A.Z.Genome biology · 2025Article
- Genome-Wide Characterization of Alfin-like Genes inPlants (Basel, Switzerland) · 2024Article
- Alfin-like (AL) transcription factor family inBiotechnology reports (Amsterdam, Netherlands) · 2024Article
- Comprehensive analysis of Alfin-like transcription factors associated with drought and salt stresses in wheat (Triticum aestivum L.).BMC genomics · 2024Article
- Genome-Wide Identification of the Alfin-like Gene Family in Cotton (Plants (Basel, Switzerland) · 2024Article
- Involvement of Alfin-Like Transcription Factors in Plant Development and Stress Response.Genes · 2024Review
- The evolution of bitter taste receptor gene in primates: Gene duplication and selection.Ecology and evolution · 2023Article
- Identification and Expression Analysis of the Alfin-like Gene Family in Tomato and the Role ofPlants (Basel, Switzerland) · 2023Article
- Genome-wide characterization of Alfin-like (AL) genes in apple and functional identification of MdAL4 in response to drought stress.Plant cell reports · 2023Article
- PHD finger proteins function in plant development and abiotic stress responses: an overview.Frontiers in plant science · 2023Review
- Carrot DcALFIN4 and DcALFIN7 Transcription Factors Boost Carotenoid Levels and Participate Differentially in Salt Stress Tolerance When Expressed inInternational journal of molecular sciences · 2022Article
- Ectopic expression of Medicago truncatula homeodomain finger protein, MtPHD6, enhances drought tolerance in Arabidopsis.BMC genomics · 2019Article
- Evolution and conservation of polycomb repressive complex 1 core components and putative associated factors in the green lineage.BMC genomics · 2019Article
- Delineating the molecular responses of a halotolerant microalga using integrated omics approach to identify genetic engineering targets for enhanced TAG production.Biotechnology for biofuels · 2019Article
- An Alfin-like gene from Atriplex hortensis enhances salt and drought tolerance and abscisic acid response in transgenic Arabidopsis.Scientific reports · 2018Article
- A Histone Code Reader and a Transcriptional Activator Interact to Regulate Genes for Salt Tolerance.Plant physiology · 2017Article
- Article
- Characterization and stress-induced expression analysis of Alfin-like transcription factors in Brassica rapa.Molecular genetics and genomics : MGG · 2015Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In previous studies, the Alfin1 gene, a transcription factor, enhanced salt tolerance in alfalfa, primarily through altering gene expression levels in the root. Here, we examined the molecular evolution of the Alfin-like (AL) proteins in two Arabidopsis species (A. lyrata and A. thaliana) and a salt-tolerant close relative Thellungiella halophila. These AL-like proteins could be divided into four groups and the two known DUF3594 and PHD-finger domains had co-evolved within each group of genes, irrespective of species, due to gene duplication events in the common ancestor of all three species while gene loss was observed only in T. halophila. To detect whether natural selection acted in the evolution of AL genes, we calculated synonymous substitution ratios (dn/ds) and codon usage statistics, finding positive selection operated on four branches and significant differences in biased codon usage in the AL family between T. halophila and A. lyrata or A. thaliana. Distinctively, only the AL7 branch was under positive selection on the PHD-finger domain and the three members on the branch showed the smallest difference when codon bias was evaluated among the seven clusters. Functional analysis based on transgenic overexpression lines and T-DNA insertion mutants indicated that salt-stress-induced AtAL7 could play a negative role in salt tolerance of A. thaliana, suggesting that adaptive evolution occurred in the members of AL gene family.
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