ArticlePloS one2013
Unbiased approach for virus detection in skin lesions.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 62 citations in OpenAlex.
- Next Generation Sequencing Approaches to Characterize the Respiratory Tract Virome.Microorganisms · 2022Review
- Metatranscriptome analysis in human papillomavirus negative cervical cancers.Scientific reports · 2022Article
- PathoLive-Real-Time Pathogen Identification from Metagenomic Illumina Datasets.Life (Basel, Switzerland) · 2022Article
- Using HPV-meta for human papillomavirus RNA quality detection.Scientific reports · 2022Article
- Explainable deep neural networks for novel viral genome prediction.Applied intelligence (Dordrecht, Netherlands) · 2022Article
- Detection of viral gene expression in risk-stratified biopsies reveals no active HPV in cutaneous squamous cell carcinoma.Experimental dermatology · 2021Article
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- Emerging role of human polyomaviruses 6 and 7 in human cancers.Infectious agents and cancer · 2021Review
- The genetic diversity of human papillomavirus types from the species Gammapapillomavirus 15: HPV135, HPV146, and HPV179.PloS one · 2021Article
- Article
- ViraMiner: Deep learning on raw DNA sequences for identifying viral genomes in human samples.PloS one · 2019Article
- HPV transcription in skin tumors.PloS one · 2019Article
- Machine Learning for detection of viral sequences in human metagenomic datasets.BMC bioinformatics · 2018Article
- Utility of high-throughput DNA sequencing in the study of the human papillomaviruses.Virus genes · 2018Review
- Article
- Why Human Papillomavirus Acute Infections Matter.Viruses · 2017Review
- Evolution of selective-sequencing approaches for virus discovery and virome analysis.Virus research · 2017Review
- Genotyping of high-risk anal human papillomavirus (HPV): ion torrent-next generation sequencing vs. linear array.Virology journal · 2017Article
- Towards diagnostic metagenomics of Campylobacter in fecal samples.BMC microbiology · 2017Article
- Application of next generation sequencing for the detection of human viral pathogens in clinical specimens.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess presence of virus DNA in skin lesions, swab samples from 82 squamous cell carcinomas of the skin (SCCs), 60 actinic keratoses (AKs), paraffin-embedded biopsies from 28 SCCs and 72 kerathoacanthomas (KAs) and fresh-frozen biopsies from 92 KAs, 85 SCCs and 92 AKs were analyzed by high throughput sequencing (HTS) using 454 or Ion Torrent technology. We found total of 4,284 viral reads, out of which 4,168 were Human Papillomavirus (HPV)-related, belonging to 15 known (HPV8, HPV12, HPV20, HPV36, HPV38, HPV45, HPV57, HPV59, HPV104, HPV105, HPV107, HPV109, HPV124, HPV138, HPV147), four previously described putative (HPV 915 F 06 007 FD1, FA73, FA101, SE42) and two putatively new HPV types (SE46, SE47). SE42 was cloned, sequenced, designated as HPV155 and found to have 76% similarity to the most closely related known HPV type. In conclusion, an unbiased approach for viral DNA detection in skin tumors has found that, although some new putative HPVs were found, known HPV types constituted most of the viral DNA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.