Evidence map›Paper›PMID 23840136›Full record

ReviewWorld journal of gastroenterology2013

Caustic injury of the upper gastrointestinal tract: a comprehensive review.

Sandro Contini, Carmelo Scarpignato

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04524897 (The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children), which is not on this map. Cited by 133 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 1 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04524897 phase4unknown statusnot on this mapstarted 2020, after this paper: background citation

The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children

TypeinterventionalSponsorAssiut UniversityRan2020 to 2022Enrolled20ConditionsEsophageal StrictureArmsTriamcinolone Injection in treatment of refractory benign Esophageal Stricture in children
3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 1 synthesis or guideline pooled it, 391 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Esophageal Mucosal Injuries From Drugs, Radiation, and Caustic Agents.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Severe Corrosive Injury Secondary to Chlorine Bleach Ingestion: A Case Report.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Article

73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sandro ContiniDepartment of Surgical Sciences, University of Parma, 43125 Parma, Italy. sandrocontini46@gmail.com
Carmelo Scarpignato
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevention has a paramount role in reducing the incidence of corrosive ingestion especially in children, yet this goal is far from being reached in developing countries, where such injuries are largely unreported and their true prevalence simply cannot be extrapolated from random articles or personal experience. The specific pathophysiologic mechanisms are becoming better understood and may have a role in the future management and prevention of long-term consequences, such as esophageal strictures. Whereas the mainstay of diagnosis is considered upper gastrointestinal endoscopy, computed tomography and ultrasound are gaining a more significant role, especially in addressing the need for emergency surgery, whose morbidity and mortality remains high even in the best hands. The need to perform emergency surgery has a persistent long-term negative impact both on survival and functional outcome. Medical or endoscopic prevention of stricture is debatable, yet esophageal stents, absorbable or not, show promising data. Dilatation is the first therapeutic option for strictures and bougies should be considered especially for long, multiple and tortuous narrowing. It is crucial to avoid malnutrition, especially in developing countries where management strategies are influenced by malnutrition and poor clinical conditions. Late reconstructive surgery, mainly using colon transposition, offers the best results in referral centers, either in children or adults, but such a difficult surgical procedure is often unavailable in developing countries. Possible late development of esophageal cancer, though probably overemphasized, entails careful and long-term endoscopic screening.

Indexed as

Burns, ChemicalCausticsColonEndoscopy, GastrointestinalEsophageal NeoplasmsEsophageal StenosisHumansPlastic Surgery ProceduresPrevalenceUpper Gastrointestinal TractCausticsCaustic ingestionCorrosive strictureDeveloping countriesEndoscopic managementSurgical management

Identifiers

PMID23840136
PMCPMC3703178
OpenAlexW1985756655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.