Evidence map›Paper›PMID 23840046›Full record

ArticleThe Journal of infectious diseases2013

Obesity and human papillomavirus infection in perimenopausal women.

Su-Hsun Liu, Anne F Rositch, Raphael P Viscidi, Michelle I Silver, Anne E Burke, Patti E Gravitt

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  3. Association between body mass index, obesity, and vulvar cancer recurrence.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Su-Hsun LiuDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA. shliu@jhsph.edu
Anne F Rositch
Raphael P Viscidi
Michelle I Silver
Anne E Burke
Patti E Gravitt
Johns Hopkins University · USChang Gung Memorial Hospital · TWJohns Hopkins Bayview Medical Center · USPerdana University · MY

Funding

INSTITUTIONAL RESEARCH CANCER EPIDEMIOLOGY FELLOWSHIPT32CA009314 · NCI · JOHNS HOPKINS UNIVERSITY · PI Corinne E. Joshu, Meghan Bridgid Moran · 1985 to 2026
$11.2M
HPV Infection Among Perimenopausal Women in the 1945-64 Birth CohorR01CA123467 · NCI · JOHNS HOPKINS UNIVERSITY · PI GRAVITT, PATTI E · 2007 to 2012
$3.1M
NCI NIH HHS R01 CA123467NCI NIH HHS T32 CA0009314NCI NIH HHS T32 CA009314
6 · The paper itself

Abstract

introductionObesity is known to increase susceptibility to certain infections in men. It is unclear whether obesity increases women's risk for human papillomavirus (HPV) infection.

methodsIn a prospective cohort of 696 perimenopausal women enrolled in 2008-2012, we sought to determine whether obesity predicted incident HPV detection or nondetection. Obesity was defined as body mass index (BMI) ≥ 30 kg/m(2).

resultsBaseline any type HPV prevalence was comparable between obese and nonobese women (18.7% vs 19.1%; P > .05). Over a median follow-up period of 17.9 months (interquartile range: 12.1-24.5), 187 new HPV detections occurred among 123 women, 60 of whom subsequently lost 76 detectable infections. When compared with nonobese participants, obese women had a similar rate of new HPV detection (7.1 vs 7.8 infections per 1000 infection-years; P > .05) or loss of detection (100.3 vs 85.8 infections per 100 infection-years; P > .05). Similar results were found after adjusting for age, menopausal status, smoking habit, and sexual exposure history.

conclusionsResults from the current analysis suggest little effect of obesity on HPV detection and loss of detection in mid-adult women. More research is needed to determine whether adipokines or cytokines better capture the potential immune modulating effects of obesity on HPV infection.

Indexed as

AdultBody Mass IndexCohort StudiesFemaleHumansMiddle AgedObesityPapillomaviridaePapillomavirus InfectionsPostmenopausePremenopausePrevalenceProspective Studiesadipokinebody mass indexdiscrete-time survival analysisfrailty modelhuman papillomavirusobesitywaist circumference

Identifiers

PMID23840046
PMCPMC3762384
OpenAlexW2119757344

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.