The antidiabetic gutsy role of metformin uncovered?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes.JCI insight · 2018
   Trial
2. Role of metformin in oxaliplatin-induced peripheral neuropathy in patients with stage III colorectal cancer: randomized, controlled study.International journal of colorectal disease · 2018
   Trial
3. Metformin Toxicity Masquerading As Acute Abdomen: A Clinical Reminder of Metformin-Associated Lactic Acidosis and Its Management.Cureus · 2025
   Article
4. Viability Profiles of Normal and Cancer Bladder Cells With Metformin, Nitrate and Adenosine Monophosphate-Activated Protein Kinase Inhibitor.World journal of oncology · 2024
   Article
5. Treatment and five-year follow-up of type A insulin resistance syndrome: A case report.World journal of clinical cases · 2022
   Article
6. Alzheimer's disease and type 2 diabetes mellitus: Pathophysiologic and pharmacotherapeutics links.World journal of diabetes · 2021
   Review
7. Metformin prevents DMH-induced colorectal cancer in diabetic rats by reversing the warburg effect.Cancer medicine · 2015
   Article
8. Predicting Clostridium difficile infection in diabetic patients and the effect of metformin therapy: a retrospective, case-control study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
   Article
9. Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice.Diabetology & metabolic syndrome · 2015
   Article
10. Alcoholic and non-alcoholic steatohepatitis.Experimental and molecular pathology · 2014
    Review
11. Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain.Biochimica et biophysica acta · 2014
    Review

Corrections and comments

• Comment on
  An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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