Evidence map›Paper›PMID 23839596›Full record

ReviewNature reviews. Neuroscience2013

Shaping the nervous system: role of the core planar cell polarity genes.

Fadel Tissir, André M Goffinet

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 126 citations in OpenAlex.

  1. Article
  2. Article
  3. Emerging insights into primary ciliary dyskinesia-associated hydrocephalus: a scoping review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  4. Article
  5. Article
  6. Pathogenic variants in autism geneProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Wiring the senses: Factors that regulate peripheral axon pathfinding in sensory systems.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Review
  12. Review
  13. Article
  14. Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  15. Review
  16. Neuron-Specific Deletion ofFrontiers in genetics · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fadel TissirUniversity of Louvain, Institute of Neuroscience, Developmental Neurobiology Group, Avenue Mounier 73, Box B1.73.16, 1200 Brussels, Belgium.
André M Goffinet
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Planar cell polarity (PCP) is complementary to the intrinsic polarization of single cells and refers to the global coordination of cell behaviour in the plane of a tissue and, by extension, to the signalling pathways that control it. PCP is most evident in cell sheets, and research into PCP was for years confined to studies in Drosophila melanogaster. However, PCP has more recently emerged as an important phenomenon in vertebrates, in which it regulates various developmental processes and is associated with multiple disorders. In particular, core PCP genes are crucial for the development and function of the nervous system. They are involved in neural tube closure, ependymal polarity, neuronal migration, dendritic growth and axon guidance.

Indexed as

AnimalsBody PatterningCell MovementCell PolarityMembrane ProteinsModels, BiologicalNervous SystemNeuronsSignal TransductionMembrane Proteins

Identifiers

PMID23839596
OpenAlexW2057080394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.