Evidence map›Paper›PMID 23839578›Full record

ReviewNature reviews. Molecular cell biology2013

Role of the extracellular matrix in regulating stem cell fate.

Fiona M Watt, Wilhelm T S Huck

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 334 papers.

0numbers the graph read from it
0cells of the map it votes in
334citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

334 citing papers in PubMed.

  1. Review
  2. Article
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  11. Review
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  14. ACS nano · 2026
    Article
  15. Review
  16. Review
  17. Review
  18. Assay for Neurocan-Degrading Activity of ADAMTS-12 Metalloprotease.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  19. Article
  20. Article

274 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fiona M WattKing's College London Centre for Stem Cells and Regenerative Medicine, London, UK. fiona.watt@kcl.ac.uk
Wilhelm T S Huck

Funding

Medical Research CouncilWellcome Trust 096540
6 · The paper itself

Abstract

The field of stem cells and regenerative medicine offers considerable promise as a means of delivering new treatments for a wide range of diseases. In order to maximize the effectiveness of cell-based therapies - whether stimulating expansion of endogenous cells or transplanting cells into patients - it is essential to understand the environmental (niche) signals that regulate stem cell behaviour. One of those signals is from the extracellular matrix (ECM). New technologies have offered insights into how stem cells sense signals from the ECM and how they respond to these signals at the molecular level, which ultimately regulate their fate.

Indexed as

AnimalsCell CommunicationCell DifferentiationCell LineageExtracellular MatrixHumansMembrane FluidityModels, BiologicalStem Cell NicheStem Cells

Identifiers

PMID23839578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.