Evidence map›Paper›PMID 23839167›Full record

ReviewNutrients2013

The role of vitamin D in blood pressure, endothelial and renal function in postmenopausal women.

Zhao-Min Liu, Jean Woo, Sheng-Hui Wu, Suzanne C Ho

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Vitamin D and endothelial vasodilation in older individuals: data from the PIVUS study.The Journal of clinical endocrinology and metabolism · 2014
    Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. The association between Vitamin D and health outcomes in women: A review on the related evidence.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2016
    Review
  10. Spectacular improvement in vitamin D status in elderly osteoporotic women: 8-year analysis of an osteoporotic population treated in a dedicated fracture liaison service.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
    Article
  11. Article
  12. Review
  13. Mean platelet volume and vitamin D level.Annals of laboratory medicine · 2014
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Zhao-Min LiuDepartment of Medicine & Therapeutics, the Chinese University of Hong Kong, Hong Kong SAR 999077, China. liuzhaomin@cuhk.edu.hk
Jean Woo
Sheng-Hui Wu
Suzanne C Ho
Chinese University of Hong Kong · HKVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D is a pro-hormone that plays an essential role in the vasculature and in kidney function.

aimsTo review the extra-skeletal effects of vitamin D on blood pressure, endothelial and renal function with emphasis on recent findings in postmenopausal women.

methodsIncluded in this review was a PubMed database search for English language articles through March 2013. This review discussed the physiology and definition of vitamin D deficiency, the recent evidence for the role vitamin D in blood pressure, vascular and renal function.

resultsExperimental and epidemiological data suggest that vitamin D plays an important role in the vasculature and in kidney function. Low vitamin D concentrations appear to significantly associate with hypertension, endothelial and renal dysfunction. However, the results of clinical trials have generally been mixed. Studies specifically conducted among postmenopausal women are limited and findings are still inconsistent.

conclusionsDefinitive studies are warranted to elucidate the effects of vitamin D supplementation on vascular and renal function and a more detailed work is needed to outline the route, duration and optimal dose of supplementation. It is premature to recommend vitamin D as a therapeutic option in the improvement of vascular and renal function at the current stage.

Indexed as

Dietary SupplementsBlood PressureCardiovascular DiseasesDatabases, FactualEndotheliumFemaleGuidelines as TopicHumansHypertensionKidneyPostmenopauseRandomized Controlled Trials as TopicRenal Insufficiency, ChronicRisk FactorsVitamin DVitamin D DeficiencyVitamin D

Identifiers

PMID23839167
PMCPMC3738990
OpenAlexW2029405182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.