Evidence map›Paper›PMID 23839041›Full record

ReviewCell cycle (Georgetown, Tex.)2013

Genetic control of quiescence in hematopoietic stem cells.

Takeshi Yamada, Chun Shik Park, H Daniel Lacorazza

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell cycle (Georgetown, Tex.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  13. Single-cell sequencing reveals suppressive transcriptional programs regulated by MIS/AMH in neonatal ovaries.Proceedings of the National Academy of Sciences of the United States of America · 2021
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  19. Heterogeneity of Ly6GInfection and immunity · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Takeshi YamadaDepartment of Pathology & Immunology; Baylor College of Medicine; Texas Children's Hospital; Houston, TX USA.
Chun Shik Park
H Daniel Lacorazza
Texas Children's Hospital · USBaylor College of Medicine · US

Funding

Transcriptional Regulation of Development and Maintenance of Memory T LymphocytesR01AI077536 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI LACORAZZA, DANIEL · 2008 to 2011
$1.7M
NIAID NIH HHS R01 AI077536NIAID NIH HHS R01-AI077536NIAID NIH HHS R01-AI077536-02S1
6 · The paper itself

Abstract

Cellular quiescence is a reversible cell cycle arrest that is poised to re-enter the cell cycle in response to a combination of cell-intrinsic factors and environmental cues. In hematopoietic stem cells, a coordinated balance between quiescence and differentiating proliferation ensures longevity and prevents both genetic damage and stem cell exhaustion. However, little is known about how all these processes are integrated at the molecular level. We will briefly review the environmental and intrinsic control of stem cell quiescence and discuss a new model that involves a protein-to-protein interaction between G0S2 and the phospho-nucleoprotein nucleolin in the cytosol.

Indexed as

Gene Expression RegulationAmino Acid SequenceAnimalsCell Cycle CheckpointsCell Cycle ProteinsCell ProliferationHematopoietic Stem CellsHumansMolecular Sequence DataNucleolinPhosphoproteinsProtein BindingProtein Interaction Domains and MotifsRNA-Binding ProteinsCell Cycle ProteinsG0S2 protein, humanNucleolinPhosphoproteinsRNA-Binding ProteinsG0S2hematopoietic stem cellsquiescence

Identifiers

PMID23839041
PMCPMC3841317
OpenAlexW1986552067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.