Trial reportWorld journal of surgery2013
Quality of life (QoL) in patients with benign thyroid goiters (pre- and post-thyroidectomy): a prospective study.
Trial report in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04645056 (The Impact of Post-thyroidectomy Neck Stretching Exercises on Improving Short Term Quality of Life), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Post-thyroidectomy Neck Stretching Exercises on Improving Short Term Quality of Life: A Randomized Prospective Clinical Trial
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Quality of Life in Patients with Benign Non-Toxic Goiter After Surgical Intervention: A Systematic Review and Meta-Analysis.World journal of surgery · 2022Pooled it
- The Impact of Post-Thyroidectomy Neck Stretching Exercises on Neck Discomfort, Pressure Symptoms, Voice and Quality of Life: A Randomized Controlled Trial.World journal of surgery · 2022Trial
- The compensatory enlargement of the remaining thyroid lobe following hemithyroidectomy is small and without impact on symptom relief.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Trial
- Novel ThyPRO-39-based nomogram for identifying impaired quality of life in Graves' hyperthyroidism outpatients: development and internal validation.Endocrine connections · 2026Article
- Quality of life assessment in patients undergoing partial and total thyroidectomy.Revista do Colegio Brasileiro de Cirurgioes · 2026Article
- Impact of body mass index on neck muscle changes and postoperative outcomes in patients undergoing hemithyroidectomy: a retrospective cohort study.BMC surgery · 2025Article
- Hypothyroidism After Hemithyroidectomy: A Retrospective Analysis of Temporal Trends and Key Risk Factors.Journal of clinical medicine · 2025Article
- Trends and projections of the global burden of thyroid cancer from 1990 to 2030.Journal of global health · 2024Article
- Risk factors for difficult thyroidectomy and postoperative morbidity do not match: retrospective study from an endocrine surgery academic referral centre.Updates in surgery · 2022Article
- Impact of thyroidectomy on quality of life in benign goitres: results from a prospective cohort study.Langenbeck's archives of surgery · 2022Article
- Authors' Reply: Endoscopic versus Conventional Thyroid Surgery: a Comparison of Quality of Life, Cosmetic Outcomes and Overall Patient Satisfaction with Treatment.World journal of surgery · 2021Article
- Quality of life in obese patients after thyroidectomy for goiter.Gland surgery · 2021Article
- Quality of life among patients on levothyroxine: A cross-sectional study.Annals of medicine and surgery (2012) · 2020Article
- Endoscopic versus Conventional Thyroid Surgery: A Comparison of Quality of Life, Cosmetic Outcomes and Overall Patient Satisfaction with Treatment.World journal of surgery · 2020Article
- Does Thyroidectomy Impact Quality of Life: Retrospective Case-Control Study of Post-Thyroidectomy Patients and Matched Individuals from the General Population.Medicina (Kaunas, Lithuania) · 2020Article
- Evaluation of Quality of Life in Patients with Differentiated Thyroid Cancer by Means of the Thyroid-Specific Patient-Reported Outcome Questionnaire: A 5-Year Longitudinal Study.European thyroid journal · 2020Article
- Quality of life is not affected by thyroid surgery in nontoxic benign goitre in long-term surveillance-A prospective observational study.Endocrinology, diabetes & metabolism · 2020Article
- Changes in Swallowing Symptoms and Esophageal Motility After Thyroid Surgery: A Prospective Cohort Study.World journal of surgery · 2018Article
- Nontoxic Goiter (NTG) and Radioiodine: What Do Patients Think About It? Quality of Life in Patients with NTG Before and After 131-I Therapy.Frontiers in endocrinology · 2018Article
- Relationship between age and outcome in thyroid surgery: a prospective observational study.Innovative surgical sciences · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreservation of quality of life (QoL) seems an important therapeutic goal in patients with benign thyroid diseases. The aim of the present study was to investigate the impact of thyroidectomy on QoL in patients with benign goiters and to assess the significance of various factors affecting the outcome.
methodsA prospective study consisting of 100 patients with benign goiters was conducted between November 2009 and March 2011. Patients completed a disease-specific ThyPRO questionnaire to assess QoL before and 6 months after thyroidectomy. Preoperative and postoperative scores were compared; and univariate and multivariate analyses were performed.
resultsMean age of the patients was 40.5 years (M:F = 1:4.3); 82 % of the patients had nodular goiters, and the remaining 18 % had diffuse disease. None of the patients had overt thyroid dysfunction at the time they completed the questionnaire. Operative treatment for 54 % of the patients involved total thyroidectomy, whereas 46 % underwent hemithyroidectomy. None of these patients developed any permanent morbidity following surgery. Mean scores of QoL in the 12 domains examined were low and improved significantly (p < 0.001) after surgery: symptoms, 19.4 versus 0.7; fatigue, 29.5 versus 1.5; vitality, 44.4 versus 3.0; memory and concentration, 25.7 versus 1.5; nervousness, 29.6 versus 1.8; psychological well-being, 33.9 versus 1.3; mood swings, 34.9 versus 0.8; relationship, 15.4 versus 1.4; daily activity, 18.7 versus 1.3; sex life, 20.9 versus 1.7; appearance, 14.7 versus 1.0; and overall, 27 versus 5.5. On univariate analysis, weight of goiter was found to be significantly associated with improvement in the scores of the memory and concentration domain (p = 0.03). On multivariate analysis, factors significantly associated with improvement in different domains were young age (nervousness, p = 0.009), female gender (fatigue, p = 0.02), and weight of goiter (symptoms, p = <0.001; vitality, p = <0.001; and memory and concentration, p = <0.001).
conclusionsPatients with benign goiters experience significant improvement in QoL after thyroidectomy.
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