Evidence map›Paper›PMID 23837833›Full record

Trial reportImplementation science : IS2013

Improvement of hospital care for patients with non-Hodgkin's lymphoma: protocol for a cluster randomized controlled trial (PEARL study).

Jozette J C Stienen, Rosella P M G Hermens, Lianne Wennekes, Saskia A M van de Schans, Helena M Dekker, Nicole M A Blijlevens, Richard W M van der Maazen, Eddy M M Adang, Johan H J M van Krieken, Petronella B Ottevanger

Registry-linked trialOpen access · goldAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Implementation science : IS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01562509 (Improvement of Hospital Care for Patients With Non-Hodgkin's Lymphoma), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01562509 naunknown statusnot on this map

Improvement of Hospital Care for Patients With Non-Hodgkin's Lymphoma

TypeinterventionalSponsorRadboud University Medical CenterRan2012 to 2014Enrolled418ConditionsNon-Hodgkin LymphomaArmsImplementation tools, Standard intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jozette J C StienenScientific Institute for Quality of Healthcare IQ healthcare, Radboud University Nijmegen Medical Centre, PO box 9101, 6500 HB Nijmegen the Netherlands. J.Stienen@iq.umcn.nl
Rosella P M G Hermens
Lianne Wennekes
Saskia A M van de Schans
Helena M Dekker
Nicole M A Blijlevens
Richard W M van der Maazen
Eddy M M Adang
Johan H J M van Krieken
Petronella B Ottevanger
Radboud University Medical Center · NLRadboud University Nijmegen · NLNetherlands Comprehensive Cancer Organisation · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalignant lymphomas constitute a diverse group of cancers of lymphocytes. One well-known disease is Hodgkin's lymphoma; the others are classified as non-Hodgkin's lymphoma (NHL). NHLs are the most common hematologic neoplasms in adults worldwide, and in 2012 over 170,000 new cases were estimated in the United States and Europe.In previous studies, several practice gaps in hospital care for patients with NHL have been identified. To decrease this variation in care, the present study aims to perform a problem analysis in which barriers to and facilitators for optimal NHL care will be identified and, based on these findings, to develop (tailored) improvement strategies. Subsequently, we will assess the effectiveness, feasibility and costs of the improvement strategies. METHODS/

designBarriers and facilitators will be explored using the literature, using interviews and questionnaires among physicians involved in NHL care, and patients diagnosed with NHL. The results will be used to develop a tailored improvement strategy. A cluster randomized controlled trial involving 19 Dutch hospitals will be conducted. Hospitals will be randomized to receive either an improvement strategy tailored to the barriers and facilitators found or, a standard strategy of audit and feedback.The effects of both strategies will be evaluated using previously developed quality indicators. Adherence to the indicators will be measured before and after the intervention period based on medical records from newly diagnosed NHL patients. To study the feasibility of both strategies, a process evaluation will be additionally performed. Data about exposure to the different elements of the strategies will be collected using questionnaires. Economic evaluation from a healthcare perspective will compare the two implementation strategies, where the costs of the implementation strategy and changes in healthcare consumption will be assessed. DISCUSSION: The presence of variation in the use of diagnostic tests, treatment, and follow-up between different physicians in different hospitals in the Netherlands is important for patients. To reduce the existing variation in care, implementation of tailored interventions to improve NHL care is necessary.

trial registrationThis trial is registered at ClinicalTrial.gov as the PEARL study, registration number NCT01562509.

Indexed as

HospitalizationAdolescentAdultAgedCluster AnalysisCosts and Cost AnalysisFeasibility StudiesGuideline AdherenceHumansLymphoma, Non-HodgkinMiddle AgedNetherlandsPractice Guidelines as TopicQuality ImprovementYoung Adult

Identifiers

PMID23837833
PMCPMC3711783
OpenAlexW2122409229

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.