ArticleClinical and molecular hepatology2013
Predictive factors that influence the survival rates in liver cirrhosis patients with spontaneous bacterial peritonitis.
Article in Clinical and molecular hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- An Epidemiological Meta-Analysis on the Worldwide Prevalence, Resistance, and Outcomes of Spontaneous Bacterial Peritonitis in Cirrhosis.Frontiers in medicine · 2021Pooled it
- KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications.Clinical and molecular hepatology · 2018Guideline
- Article
- From dysbiosis to prediction: a novel gut microbiota-derived index for spontaneous bacterial peritonitis in HBV-related cirrhosis.Frontiers in immunology · 2026Article
- Bacterial profile, drug resistance pattern, clinical and laboratory predictors of ascites infection in cirrhosis patients.BMC infectious diseases · 2024Article
- Initial treatment response and short-term mortality of spontaneous bacterial peritonitis in cirrhotic patients with hepatocellular carcinoma.Scientific reports · 2023Article
- Spontaneous bacterial peritonitis in hepatocellular carcinoma after PD-1 inhibitor therapy: two clinical cases.Heliyon · 2022Article
- Development and Validation of a Prognostic Model for One-year Survival of Cirrhosis Patients with First-ever Spontaneous Bacterial Peritonitis.Journal of clinical and translational hepatology · 2021Article
- Article
- Spontaneous bacterial peritonitis mortality trends of cirrhotic patients in the last decade in Constanta County.Experimental and therapeutic medicine · 2021Article
- Multivariate predictive model for asymptomatic spontaneous bacterial peritonitis in patients with liver cirrhosis.World journal of gastroenterology · 2020Article
- Short- and long-term predictors of spontaneous bacterial peritonitis in Singapore.Singapore medical journal · 2020Article
- [Severe liver disease combined by fungal infection].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020Article
- Spontaneous bacterial peritonitis in patients with cirrhosis: incidence, outcomes, and treatment strategies.Hepatic medicine : evidence and research · 2019Review
- Prognosis of Spontaneous Bacterial Peritonitis in Hepatocellular Carcinoma Patients.Journal of Korean medical science · 2018Article
- Bacterascites: A study of clinical features, microbiological findings, and clinical significance.Liver international : official journal of the International Association for the Study of the Liver · 2018Article
- Clinical and bacteriological features and prognosis of ascitic fluid infection in Chinese patients with cirrhosis.BMC infectious diseases · 2018Article
- Follow-up Creatinine Level Is an Important Predictive Factor of In-hospital Mortality in Cirrhotic Patients with Spontaneous Bacterial Peritonitis.Journal of Korean medical science · 2018Article
- Spontaneous bacterial and fungal peritonitis in patients with liver cirrhosis: A literature review.World journal of hepatology · 2018Review
- [End-stage liver disease and invasive fungal infection].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2018Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsSpontaneous bacterial peritonitis (SBP) has been known to greatly influence the survival rate of patients with liver cirrhosis. However, the factors that affect the survival rate in patients with SBP need to be clarified.
methodsThis study enrolled 95 liver cirrhosis patients diagnosed with SBP. The laboratory findings of their serum and ascitic fluid were examined and the characteristics of the isolated microorganisms in their peritoneal fluid were analyzed.
resultsThe proportion of patients with culture-positive SBP was 41.1%, and 47 microorganisms were isolated from the ascitic fluid. The proportions of cultured bacteria that were Gram negative and Gram positive were 57.4% and 40.4%, respectively. The proportions of Escherichia coli, Klebsiella species, and Streptococcus species were 25.5%, 19.1%, and 19.1%, respectively. Enterococcus species represented 12.8% of the microorganisms cultured. The overall survival rates at 6, 12, and 24 months were 44.5%, 37.4%, and 32.2%, respectively. There was no relationship between the bacterial factors and the survival rate in SBP. Multivariate analysis revealed that the presence of hepatocellular carcinoma (HCC; P=0.001), higher serum bilirubin levels (≥3 mg/dL, P=0.002), a prolonged serum prothrombin time (i.e., international normalized ratio >2.3, P<0.001), renal dysfunction (creatinine >1.3 mg/dL, P<0.001), and lower glucose levels in the ascitic fluid (<50 mg/dL, P<0.001) were independent predictive factors of overall survival rate.
conclusionsHCC, higher serum bilirubin levels, a prolonged serum prothrombin time, renal dysfunction, and lower ascitic glucose levels are associated with higher mortality rates in cirrhotic patients with SBP.
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