Evidence map›Paper›PMID 23837085›Full record

ArticleDeutsches Arzteblatt international2013

Take home maintenance medication in opiate dependence.

Stefan Gutwinski, Lena Karoline Bald, Andreas Heinz, Christian A Müller, Ane Katrin Schmidt, Corinde Wiers, Felix Bermpohl, Jürgen Gallinat

Abstract readMulticenter Study
In one paragraph

Article in Deutsches Arzteblatt international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Dispensing maintenance medication to take home not allowed.Deutsches Arzteblatt international · 2013
    Article
  8. In reply.Deutsches Arzteblatt international · 2013
    Article
  9. Not registered.Deutsches Arzteblatt international · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Stefan GutwinskiPsychiatric University Hospital Charité, St. Hedwig Hospital, Berlin, Germany. Stefan.Gutwinski@charite.de
Lena Karoline Bald
Andreas Heinz
Christian A Müller
Ane Katrin Schmidt
Corinde Wiers
Felix Bermpohl
Jürgen Gallinat
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpiate-dependent patients can be given several days' worth of maintenance medication to take home. We studied whether the patients chosen to receive take home maintenance medication met the criteria that were published in the guidelines of the German Medical Association. These include, among other things: abstinence from additional consumption of heath-endangering substances, psychosocial reintegration, completion of the switch from illegal narcotics to the substitute maintenance medication, and clinical stabilization.

methodsIn this study, data were obtained by questionnaire over the period from May to October 2011 from patients of all 20 psychiatric hospitals and all 110 physicians' practices with licenses to provide opiate maintenance medication in Berlin, Germany.

results986 (19.9%) of the 5032 patients taking opiate medication answered the study questionnaire; 956 gave information about the frequency with which they received medication. 365 of these 956 patients (38.2%) reported having received take home medication. Among them, 197 (56.0%) said that they additionally consumed health-endangering substances, compared to 388 (69.9%) of those who received maintenance medication every day (p<0.0001). Lower rates of additional consumption among recipients of take home maintenance medication were also found for each of the substances heroin, cocaine, and benzodiazepines (p<0.0001 for each). Patients receiving take home medication more commonly indicated that they were employed and tended to have been in the maintenance program longer than patients receiving maintenance medication every day (p<0.0001 for each question). Clinical stabilization, i.e., improvement of mental and physical health, was reported in equal measure by patients who were and were not receiving take home medication.

conclusionThe patient questionnaire reveals that most patients receiving take home maintenance medication meet the criteria specified in the guidelines of the German Medical Association.

Indexed as

Quality of LifeAdolescentAdultAgedFemaleGermanyHumansMaintenance ChemotherapyMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPrescriptionsPrevalenceRisk AssessmentMethadone

Identifiers

PMID23837085
PMCPMC3702025
OpenAlexW2106687286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.