Evidence map›Paper›PMID 23836542›Full record

ArticleCurrent protocols in chemical biology2010

Construction and use of glycan microarrays.

Christopher T Campbell, Yalong Zhang, Jeffrey C Gildersleeve

Abstract read
In one paragraph

Article in Current protocols in chemical biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 49 citations in OpenAlex.

  1. Trial
  2. Humoral response to a viral glycan correlates with survival on PROSTVAC-VF.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Trial
  3. Article
  4. Article
  5. Stereoselective Synthesis of Sialyl LewisAngewandte Chemie (International ed. in English) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. EnterotoxigenicInfection and immunity · 2022
    Article
  11. General Strategies for Glycan Microarray Data Processing and Analysis.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christopher T CampbellNational Cancer Institute, Frederick, Maryland.
Yalong Zhang
Jeffrey C Gildersleeve
National Cancer Institute · US

Funding

Development of a Carbohydrate MicroarrayZIABC010675 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GILDERSLEEVE, JEFFREY · 2009 to 2025
$6.1M
Development of a Carbohydrate MicroarrayZ01BC010675 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GILDERSLEEVE, JEFF · 2005 to 2008
$438k
Intramural NIH HHS Z01 BC010675
6 · The paper itself

Abstract

Glycosylation is an important post-translational modification that influences many biological processes critical for development, normal physiologic function, and diseases. Unfortunately, progress toward understanding the roles of glycans in biology has been slow due to the challenges of studying glycans and the proteins that interact with them. Glycan microarrays provide a high-throughput approach for the rapid analysis of carbohydrate-macromolecule interactions. Protocols detailed here are intended to help laboratories with basic familiarity of DNA or protein microarrays to begin printing and performing assays using glycan microarrays. Basic and advanced data processing are also detailed, along with strategies for improving reproducibility of data collected with glycan arrays. Curr. Protoc. Chem Biol. 2:37-53. © 2010 by John Wiley & Sons, Inc.

Indexed as

carbohydrate‐dependent bindingglycosylationmicroarrayneoglycoconjugateserum antibody profile

Identifiers

PMID23836542
PMCPMC4533865
OpenAlexW1845522298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.