ArticleHippocampus2013
Lateral entorhinal cortex is necessary for associative but not nonassociative recognition memory.
Article in Hippocampus, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
- Chronic Electroconvulsive Shock Disrupts Hippocampal Physiology and Impairs Associative Memory in Mice.Hippocampus · 2026Article
- Article
- Coordinating Cognition: The Entorhinal Cortex in Mnemonic, Temporal and Spatial Representation.Cells · 2026Review
- GATE: Adaptive learning with working memory by information gating in multi-lamellar hippocampal formation.PLoS computational biology · 2026Article
- The entorhinal spatial map integrates visual identity information of landmarks.Nature communications · 2026Article
- Lateral entorhinal cortex supports behaviorally-induced hippocampal ensemble stability for reliable memory recall.bioRxiv : the preprint server for biology · 2026Article
- The circuitry regulation of associative learning: dissociated and integrated function of the perirhinal cortex and hippocampus.Frontiers in neural circuits · 2026Review
- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
- Brief sleep disruption following hippocampus-dependent learning downscales interneuron synapses within lateral entorhinal cortex.bioRxiv : the preprint server for biology · 2025Article
- Rearing Behavior as Indicator of Spatial Novelty and Memory in Developing Rats.The European journal of neuroscience · 2025Article
- Object-translocation induces event coding in the rat hippocampus.Communications biology · 2025Article
- Neural circuits for goal-directed navigation across species.Trends in neurosciences · 2024Review
- The medial entorhinal cortex encodes multisensory spatial information.Cell reports · 2024Article
- Object-place-context learning impairment correlates with spatial learning impairment in aged Long-Evans rats.Hippocampus · 2024Article
- Direct cortical inputs to hippocampal area CA1 transmit complementary signals for goal-directed navigation.Neuron · 2023Article
- Beyond Correlation: Optimal Transport Metrics For Characterizing Representational Stability and Remapping in Neurons Encoding Spatial Memory.bioRxiv : the preprint server for biology · 2023Article
- Resilience in Mild Cognitive Impairment (MCI): Examining the Level and the Associations of Resilience with Subjective Wellbeing and Negative Affect in Early and Late-Stage MCI.Behavioral sciences (Basel, Switzerland) · 2023Article
- A Ventromedial Prefrontal-to-Lateral Entorhinal Cortex Pathway Modulates the Gain of Behavioral Responding During Threat.Biological psychiatry · 2023Article
- Superficial-layer versus deep-layer lateral entorhinal cortex: Coding of allocentric space, egocentric space, speed, boundaries, and corners.Hippocampus · 2023Article
- Limbic progesterone receptors regulate spatial memory.Scientific reports · 2023Article
17 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
Abstract
The lateral entorhinal cortex (LEC) provides one of the two major input pathways to the hippocampus and has been suggested to process the nonspatial contextual details of episodic memory. Combined with spatial information from the medial entorhinal cortex it is hypothesised that this contextual information is used to form an integrated spatially selective, context-specific response in the hippocampus that underlies episodic memory. Recently, we reported that the LEC is required for recognition of objects that have been experienced in a specific context (Wilson et al. (2013) Hippocampus 23:352-366). Here, we sought to extend this work to assess the role of the LEC in recognition of all associative combinations of objects, places and contexts within an episode. Unlike controls, rats with excitotoxic lesions of the LEC showed no evidence of recognizing familiar combinations of object in place, place in context, or object in place and context. However, LEC lesioned rats showed normal recognition of objects and places independently from each other (nonassociative recognition). Together with our previous findings, these data suggest that the LEC is critical for associative recognition memory and may bind together information relating to objects, places, and contexts needed for episodic memory formation.
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