ReviewJournal of applied toxicology : JAT2014
Environmental epigenetics: from novelty to scientific discipline.
Review in Journal of applied toxicology : JAT, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Introducing the EpGEpigenomes · 2025Article
- Development and validation of an epigenetic signature of allostatic load.Bioscience reports · 2025Article
- Factors influencing brain recovery from stroke via possible epigenetic changes.Future science OA · 2024Review
- Racial/ethnic disparities in gastric cancer: A 15-year population-based analysis.Cancer medicine · 2023Article
- Precision Medicine and Public Health: New Challenges for Effective and Sustainable Health.Journal of personalized medicine · 2021Review
- DNA methylome signatures as epigenetic biomarkers of hexanal associated with lung toxicity.PeerJ · 2021Article
- Association between H3K36me3 modification and methylation ofToxicology research · 2020Article
- Adherence to the Mediterranean diet partially mediates socioeconomic differences in leukocyte LINE-1 methylation: evidence from a cross-sectional study in Italian women.Scientific reports · 2020Article
- How Dietary Factors Affect DNA Methylation: Lesson from Epidemiological Studies.Medicina (Kaunas, Lithuania) · 2020Review
- Atti Le giornate della ricerca scientificae delle esperienze professionali dei giovani: Società Italiana di Igiene, Medicina Preventiva e Sanità Pubblica (SItI) Roma 20-21 dicembre 2019.Journal of preventive medicine and hygiene · 2020Article
- Ethical Issues in Research and Development of Epigenome-wide Technologies.Epigenetics insights · 2020Article
- Dietary Patterns are Associated with Leukocyte LINE-1 Methylation in Women: A Cross-Sectional Study in Southern Italy.Nutrients · 2019Article
- The Many Faces of EpigeneticsOxford, December 2017.Epigenetics · 2019Article
- Prenatal maternal antidepressants, anxiety, and depression and offspring DNA methylation: epigenome-wide associations at birth and persistence into early childhood.Clinical epigenetics · 2019Article
- DNA methylation signatures as biomarkers of prior environmental exposures.Current epidemiology reports · 2019Article
- Impact of CAR Agonist Ligand TCPOBOP on Mouse Liver Chromatin Accessibility.Toxicological sciences : an official journal of the Society of Toxicology · 2018Article
- Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.International journal of epidemiology · 2018Article
- Mediterranean Diet and Particulate Matter Exposure Are Associated With LINE-1 Methylation: Results From a Cross-Sectional Study in Women.Frontiers in genetics · 2018Article
- Air Pollution and the Epigenome: A Model Relationship for the Exploration of Toxicoepigenetics.Current opinion in toxicology · 2017Article
- Bi-directional effects of vitamin BScientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Epigenetic phenomena have sparked much interest resulting in an exponential increase in scientific investigation in the last two decades. While growing, the field of environmental epigenetics remains small when compared to other areas of epigenetic inquiry such as cancer research. In this paper, our objective is to describe the status of the field of environmental epigenetics and lay out our vision for its future. While environmental epigenetic studies represent fewer than 5% of all epigenetic publications, the National Institute of Environmental Health Sciences ranks second in proportion of dollars spent on epigenetics of all NIH Institutes. Such investment highlights the hypothesis that epigenetic marks are modified by environmental exposures and the hope that interventions targeted at epigenetic mechanisms may ultimately lead to improved health outcomes. The road to achieve this vision will require: (1) attention to tissue specificity; (2) focused interventional studies; (3) collaboration among cohorts; (4) inclusion of environmental exposures in new large-scale epigenomic studies; and (5) understanding of multiple mechanisms beyond DNA methylation and histone modifications. The investment in environmental epigenetic inquiry will lead to great rewards if we can understand the biology of how phenotype results from environmental stimuli and genetic code. Understanding the epigenetic implications of our actions and exposures may benefit generations to come.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.