BCAT1 defines gliomas by IDH status.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Branched-Chain Amino Acids and Seizures: A Systematic Review of the Literature.CNS drugs · 2019
   Pooled it
2. The promise of mitochondria in the treatment of glioblastoma: a brief review.Discover oncology · 2025
   Review
3. The mechanism of branched-chain amino acid transferases in different diseases: Research progress and future prospects.Frontiers in oncology · 2022
   Review
4. Differential expression of the BCAT isoforms between breast cancer subtypes.Breast cancer (Tokyo, Japan) · 2021
   Article
5. Isocitrate dehydrogenase variants in cancer - Cellular consequences and therapeutic opportunities.Current opinion in chemical biology · 2020
   Review
6. MR-detectable metabolic biomarkers of response to mutant IDH inhibition in low-grade glioma.Theranostics · 2020
   Article
7. BCAT1 is a New MR Imaging-related Biomarker for Prognosis Prediction in IDH1-wildtype Glioblastoma Patients.Scientific reports · 2017
   Article
8. Journal of neuro-oncology · 2017
   Article
9. Glioma: experimental models and reality.Acta neuropathologica · 2017
   Review
10. Assessment of bevacizumab resistance increased by expression of BCAT1 in IDH1 wild-type glioblastoma: application of DSC perfusion MR imaging.Oncotarget · 2016
    Article
11. MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.Topics in magnetic resonance imaging : TMRI · 2016
    Review
12. Predicting the likelihood of an isocitrate dehydrogenase 1 or 2 mutation in diagnoses of infiltrative glioma.Neuro-oncology · 2014
    Article
13. The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells.Acta neuropathologica · 2014
    Article
14. The role of branched-chain aminotransferase 1 in driving glioblastoma cell proliferation and invasion varies with tumor subtype.Neuro-oncology advances
    Article

Corrections and comments

• Comment on
  BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.2013

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as