Evidence map›Paper›PMID 23836162›Full record

ArticleMagma (New York, N.Y.)2014

Application of kt-BLAST acceleration to reduce cardiac MR imaging time in healthy and infarcted mice.

Ian Marshall, Maurits A Jansen, Yuehui Tao, Gavin D Merrifield, Gillian A Gray

Abstract read
In one paragraph

Article in Magma (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ian MarshallCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK, ian.marshall@ed.ac.uk.
Maurits A Jansen
Yuehui Tao
Gavin D Merrifield
Gillian A Gray

Funding

Medical Research Council G0700695Medical Research Council MRC G0700695
6 · The paper itself

Abstract

objectWe evaluated the use of kt-broad-use linear acquisition speed-up technique (kt-BLAST) acceleration of mouse cardiac imaging in order to reduce scan times, thereby minimising physiological variation and improving animal welfare. MATERIALS AND

methodsConventional cine cardiac MRI data acquired from healthy mice (n = 9) were subsampled to simulate kt-BLAST acceleration. Cardiological indices (left ventricular volume, ejection fraction and mass) were determined as a function of acceleration factor. kt-BLAST threefold undersampling was implemented on the scanner and applied to a second group of mice (n = 6 healthy plus 6 with myocardial infarct), being compared with standard cine imaging (3 signal averages) and cine imaging with one signal average.

resultsIn the simulations, sufficient accuracy was achieved for undersampling factors up to three. Cardiological indices determined from the implemented kt-BLAST scanning showed no significant differences compared with the values determined from the standard sequence, and neither did indices derived from the cine scan with only one signal average despite its lower signal-to-noise ratio. Both techniques were applied successfully in the infarcted hearts.

conclusionFor cardiac imaging of mice, threefold undersampling of kt-space, or a similar reduction in the number of signal averages, are both feasible with subsequent reduction in imaging time.

Indexed as

AlgorithmsSignal Processing, Computer-AssistedAnimalsImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance Imaging, CineMaleMiceMice, Inbred C57BLMyocardial InfarctionReference ValuesReproducibility of ResultsSample SizeSensitivity and SpecificityTime FactorsVentricular Dysfunction, Left

Identifiers

PMID23836162
PMCPMC4042009

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