ArticleHeart and vessels2014
The autopsy study of 553 cases of sudden cardiac death in Chinese adults.
Article in Heart and vessels, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 47 citations in OpenAlex.
- Cardiac deaths with structural heart abnormalities in the young (0-49 years): a ten-year forensic autopsy review.Forensic science, medicine, and pathology · 2026Article
- Emergency response for maritime sudden cardiac death: framework for pre-hospital rescue procedures and analysis of clinical characteristics.Frontiers in cardiovascular medicine · 2026Article
- Review
- Global burden of myocarditis in adolescents and young adults, 1990-2019.BMC cardiovascular disorders · 2025Article
- Sudden cardiac arrest mortality in China: temporal trends and risk factors.Military Medical Research · 2025Article
- Sudden Cardiac Death-Etiology, Risk Factors and Demographic Characteristics: An Extensive Study of 1618 Forensic Autopsies.Diseases (Basel, Switzerland) · 2024Article
- Autopsy of all young sudden death cases is important to increase survival in family members left behind.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Review
- Article
- Brugada Syndrome as a Major Cause of Sudden Cardiac Death in Asians.JACC. Asia · 2022Review
- CircSLC8A1 and circNFIX can be used as auxiliary diagnostic markers for sudden cardiac death caused by acute ischemic heart disease.Scientific reports · 2021Article
- Global, Regional, and National Burden of Myocarditis From 1990 to 2017: A Systematic Analysis Based on the Global Burden of Disease Study 2017.Frontiers in cardiovascular medicine · 2021Article
- Strategy for postmortem diagnosis of myocardial infarction.Virchows Archiv : an international journal of pathology · 2020Article
- The Expression of BNP, ET-1, and TGF-β1 in Myocardium of Rats with Ventricular Arrhythmias.International journal of molecular sciences · 2019Article
- Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis.Iranian journal of basic medical sciences · 2019Article
- Sudden cardiac death caused by myocarditis in persons aged 1-49 years: a nationwide study of 14 294 deaths in Denmark.Forensic sciences research · 2019Article
- Prevalence and pattern of cardiovascular-related causes of out-of- hospital deaths in Lagos, Nigeria.African health sciences · 2018Article
- T-cell immunity in myocardial inflammation: pathogenic role and therapeutic manipulation.British journal of pharmacology · 2017Review
- Retrospective analysis of 769 cases of sudden cardiac death from 2006 to 2015: a forensic experience in China.Forensic science, medicine, and pathology · 2017Article
- Fat deposition in the left ventricle: descriptive and observacional study in autopsy.Lipids in health and disease · 2017Article
- Phosphorylated Myosin Light Chain 2 (p-MLC2) as a Molecular Marker of Antemortem Coronary Artery Spasm.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
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Authors and funding
10 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite a recent epidemiological study reporting a lower incidence of sudden cardiac death (SCD) in China as compared with that in Western countries, the exact causes of SCD are still unknown. Using a uniform review protocol and diagnostic criteria, a retrospective autopsy study identified 553 cases of SCD in 14,487 consecutive autopsies from eight regions in China representing different geographic and population features. Their ages ranged from 18 to 80 years (median 43.0 years) with a ratio of 4.3/1.0 for male/female. Out-of-hospital deaths and unwitnessed cases accounted for 74.3 and 22.6 %, respectively. The main causes of death were coronary atherosclerotic disease (CAD 50.3 %), myocarditis (14.8 %), and hypertrophic cardiomyopathy (4.5 %), with unexplained sudden death accounting for 12.1 % of the cases. CAD had a proportion of 10.4 % in victims <35 years, lower as compared with 59.0 and 83.0 % in victims aged 35-54 and in victims ≥55 years. On the other hand, myocarditis and unexplained sudden death were major causes and accounted for 34.7 and 22.5 % in victims <35 years. In order to differentiate the degree of the cause-effect relationship between autopsy findings and sudden death, a grading method was used in this series and characterized 24.3 % of findings as certain, 52.9 % as highly probable, and 22.8 % as uncertain. Our data indicated that there most likely are less CAD but more myocarditis and unexplained sudden death in Chinese youth with SCD than in populations from Western countries. Molecular genetic testing should be conducted in those cases with uncertain findings and unexplained sudden death in routine autopsy.
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