ArticleThe Clinical journal of pain2013
Days with pain and substance use disorders: is there an association?
Article in The Clinical journal of pain, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Chronic pain in a modern virally suppressed HIV cohort is associated with disability and poorer mental health.Scientific reports · 2026Observational
- Article
- A conceptual framework for the intersection of hyperalgesia and hyperkatifeia in alcohol addiction.Alcohol (Fayetteville, N.Y.) · 2025Review
- Patterns of shared genetic risk between chronic pain, psychopathologies, and neuroticism.Clinical psychological science : a journal of the Association for Psychological Science · 2025Article
- Article
- Adolescent predictors of substance use in young adulthood among individuals with childhood-onset chronic pain: A follow-up study.European journal of pain (London, England) · 2025Observational
- Physicians' perception about predictors of opioid abuse in patients with chronic non-cancer pain: a Delphi study.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Does Socioeconomic Status or Methamphetamine Use Affect Discharge Opioid Requirements in Burn-Injured Patients?Journal of burn care & research : official publication of the American Burn Association · 2022Article
- Mind-body approaches for reducing the need for post-operative opioids: Evidence and opportunities.Journal of clinical anesthesia and intensive care · 2022Article
- Prevalence and Risk Factors of Substance Use Disorder in Rheumatoid Arthritis.ACR open rheumatology · 2021Article
- Adjunctive virtual reality pain relief following traumatic injury: protocol for a randomised within-subjects clinical trial.BMJ open · 2021Article
- The effect of depressive symptoms on pain in a substance-using population with persistent pain: a cross-sectional cohort study.BMC psychiatry · 2021Article
- Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development.Pharmacological reviews · 2021Review
- Prevalence and Risk Factors of Substance Use Disorder in Inflammatory Bowel Disease.Inflammatory bowel diseases · 2021Article
- A scoping review to identify and map the multidimensional domains of pain in adults with advanced liver disease.Canadian journal of pain = Revue canadienne de la douleur · 2020Article
- Alcohol and Pain: A Translational Review of Preclinical and Clinical Findings to Inform Future Treatment Strategies.Alcoholism, clinical and experimental research · 2020Review
- Pharmacological mechanisms of alcohol analgesic-like properties in mouse models of acute and chronic pain.Neuropharmacology · 2019Article
- Effects of experimental pain induction on alcohol urge, intention to consume alcohol, and alcohol demand.Experimental and clinical psychopharmacology · 2018Article
- A prospective observational study of problematic oral cannabinoid use.Psychopharmacology · 2018Observational
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectivesWe investigated possible associations between pain frequency and the 5 most common substance use disorders: alcohol abuse/dependence, cocaine abuse/dependence, methamphetamine abuse/dependence, opioid abuse/dependence, and marijuana abuse/dependence.
methodsWe used data from the Rural Stimulant Study, a longitudinal (7 waves), observational study of at-risk stimulant users (cocaine and methamphetamine) in Arkansas and Kentucky (n=462). In fixed-effects logistic regression models, we regressed our measures of substance use disorders on the number of days with pain in the past 30 days and depression severity.
resultsTime periods when individuals had 1 to 15 days [odds ratio (OR)=1.85, P<0.001] or 16+ days (OR=2.18, P<0.001) with pain in the past 30 days were more likely to have a diagnosis of alcohol abuse/dependence, compared with time periods when individuals had no days with pain. Compared with time periods when individuals had no pain days in the past 30 days, time periods when individuals had 16+ pain days were more likely to have a diagnosis of opioid abuse/dependence (OR=3.32, P=0.02). Number of days with pain was not significantly associated with other substance use disorders. DISCUSSION: Pain frequency seems to be associated with an increased risk for alcohol abuse/dependence and opioid abuse/dependence in this population, and the magnitude of the association is medium to large. Further research is needed to investigate this in more representative populations and to determine causal relationships.
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Registered trials
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