Evidence map›Paper›PMID 23835515›Full record

ReviewCurrent opinion in chemical biology2013

New generation of oral mucosal vaccines targeting dendritic cells.

Jennifer L Owen, Bikash Sahay, Mansour Mohamadzadeh

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Pharmaceutics · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Frontiers in immunology · 2024
    Article
  8. The Bacterial Spore as a Mucosal Vaccine Delivery System.International journal of molecular sciences · 2023
    Review
  9. Current Progress and Challenges in the Study of Adjuvants for Oral Vaccines.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Influenza Virus and SARS-CoV-2 Vaccines.Journal of immunology (Baltimore, Md. : 1950) · 2021
    Review
  15. Article
  16. Oral Immunization of RecombinantFrontiers in veterinary science · 2021
    Article
  17. Article
  18. Identification of CD8αFish & shellfish immunology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer L OwenDepartment of Infectious Diseases and Pathology, University of Florida, 2015 SW16th Avenue, Gainesville, FL 32608, USA; Division of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Florida, P.O. Box 100214, Gainesville, FL 32610-0214, USA.
Bikash Sahay
Mansour Mohamadzadeh
University of Florida · US

Funding

Novel multivalent vaccine for anthrax and botulinumR01AI093370 · NIAID · UNIVERSITY OF FLORIDA · PI ZADEH, MANSOUR M · 2011 to 2015
$3.2M
NIAID NIH HHS 1R01AI098833-01NIAID NIH HHS R01 AI093370
6 · The paper itself

Abstract

As most infectious organisms gain entry at mucosal surfaces, there is a great deal of interest in developing vaccines that elicit effective mucosal immune responses against pathogen challenge. Targeted vaccination is one of the most effective methods available to prevent and control infectious diseases. Mucosal vaccines can offer lower costs, better accessibility, needle free delivery, and a higher capacity for mass immunizations during pandemics. Both local mucosal immunity and robust systemic responses can be achieved through mucosal vaccination. Recent progress in understanding the molecular and cellular components of the mucosal immune system have allowed for the development of a novel mucosal vaccine platform utilizing specific dendritic cell-targeting peptides and orally administered lactobacilli to elicit efficient antigen specific immune responses against infections, including Bacillus anthracis in experimental models of disease.

Indexed as

Immunity, MucosalAnimalsAnthraxBacillus anthracisCommunicable Disease ControlCommunicable DiseasesDendritic CellsGenetic EngineeringHumansLactobacillusPeptidesVaccinationVaccinesPeptidesVaccines

Identifiers

PMID23835515
PMCPMC3855095
OpenAlexW2009621891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.