Evidence map›Paper›PMID 23835488›Full record

ReviewNature reviews. Gastroenterology & hepatology2013

Mechanisms underlying weight loss after bariatric surgery.

Alexander D Miras, Carel W le Roux

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 164 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 11 pooled it
23.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02385617 nacompletednot on this mapstarted 2014, after this paper: background citation

Food Intake and Gut Hormone Release in Patients in Cancer Remission Who Have Undergone Upper Gastrointestinal Surgery

TypeinterventionalSponsorSt. James's Hospital, IrelandRan2014 to 2017Enrolled20ConditionsEsophageal Neoplasms, Stomach Neoplasms, Weight Loss, MalnutritionArmsOctreotide, Placebo
NCT04600596 completednot on this mapstarted 2019, after this paper: background citation

Adherence of Reporting Energy Intake by a Novel Food Photo Recognition Dietary Assessment App on Morbid Obese Subjects Scheduled for Bariatric Surgery

TypeobservationalSponsorMarco BueterRan2019 to 2023Enrolled54ConditionsObesity, Morbid, Bariatric Surgery, Roux-en-Y Gastric Bypass, Food PreferencesArmsRecording of food intake.
3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 11 syntheses or guidelines pooled it, 337 citations in OpenAlex.

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104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander D MirasMolecular and Metabolic Imaging Group, Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.
Carel W le Roux
University College Dublin · IE

Funding

Medical Research Council G0902002
6 · The paper itself

Abstract

The clinical efficacy of bariatric surgery has encouraged the scientific investigation of the gut as a major endocrine organ. Manipulation of gastrointestinal anatomy through surgery has been shown to profoundly affect the physiological and metabolic processes that control body weight and glycaemia. The most popular bariatric surgical procedures are gastric bypass, adjustable gastric banding and vertical sleeve gastrectomy. Even though these procedures were designed with the aim of causing restriction of food intake and nutrient malabsorption, evidence suggests that their contributions to weight loss are minimal. Instead, these interventions reduce body weight by decreasing hunger, increasing satiation during a meal, changing food preferences and energy expenditure. In this Review, we have explored these mechanisms as well as their mediators. The hope is that that their in-depth investigation will enable the optimization and individualization of surgical techniques, the development of equally effective but safer nonsurgical weight-loss interventions, and even the understanding of the pathophysiology of obesity itself.

Indexed as

Bariatric SurgeryComorbidityDiabetes Mellitus, Type 2Feeding BehaviorHumansObesity, MorbidWeight Loss

Identifiers

PMID23835488
OpenAlexW2077696851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.