Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2013
Long-term effects of an educational seminar on antibiotic prescribing by GPs: a randomised controlled trial.
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Association Between Antimicrobial Stewardship Programs and Antibiotic Use Globally: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Cost-effectiveness and Economic Benefit of Continuous Professional Development for Drug Prescribing: A Systematic Review.JAMA network open · 2022Pooled it
- Continuing education meetings and workshops: effects on professional practice and healthcare outcomes.The Cochrane database of systematic reviews · 2021Pooled it
- Ambulatory Antibiotic Stewardship through a Human Factors Engineering Approach: A Systematic Review.Journal of the American Board of Family Medicine : JABFMPooled it
- Factors influencing inappropriate antibiotic prescription in respiratory tract infections in general practice.Scientific reports · 2025Article
- Long-Term Effects of Individual-Focused and Team-Based Training on Health Professionals' Intention to Have Serious Illness Conversations: A Cluster Randomised Trial.Journal of CME · 2024Article
- Reporting of costs and economic impacts in randomized trials of de-implementation interventions for low-value care: a systematic scoping review.Implementation science : IS · 2023Article
- Is Education Alone Enough to Sustain Improvements of Antimicrobial Stewardship in General Practice in Australia? Results of an Intervention Follow-Up Study.Antibiotics (Basel, Switzerland) · 2023Article
- Educational Interventions to Reduce Prescription and Dispensing of Antibiotics in Primary Care: A Systematic Review of Economic Impact.Antibiotics (Basel, Switzerland) · 2022Review
- Antibiotic stewardship knowledge and belief differences among healthcare professionals in hospitals: A survey study.Heliyon · 2021Article
- A randomised controlled trial to reduce highest priority critically important antimicrobial prescription in companion animals.Nature communications · 2021Article
- The effectiveness of a simple antimicrobial stewardship intervention in general practice in Australia: a pilot study.BMC infectious diseases · 2020Article
- Communication training and the prescribing pattern of antibiotic prescription in primary health care.PloS one · 2020Article
- Attitude and perception of medical interns about antimicrobial resistance: a multi center cross-sectional study in Ethiopia.Antimicrobial resistance and infection control · 2018Article
- Educational effectiveness, target, and content for prudent antibiotic use.BioMed research international · 2015Review
- Antibiotic Resistance: What are the Opportunities for Primary Care in Alleviating the Crisis?Frontiers in public health · 2015Review
- Antibiotic overprescribing: who are the bad guys?The British journal of general practice : the journal of the Royal College of General Practitioners · 2013Article
- Antibiotics: time to act.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh levels of outpatient antibiotic use remain observed in many European countries. Several studies have shown a strong relationship between antibiotic use and bacterial resistance.
aimTo assess the long-term effect of a standardised educational seminar on antibiotic prescriptions by GPs. DESIGN AND
settingRandomised controlled trial of 171 GPs (of 203 initially randomised) in France.
methodGPs in the control group (n = 99) received no antibiotic prescription recommendation. Intervention group GPs (n = 72) attended an interactive seminar presenting evidence-based guidelines on antibiotic prescription for respiratory infections. The proportion of prescriptions containing an antibiotic in each group and related costs were compared to the baseline up to 30 months following the intervention. Data were obtained from the National Health Insurance System database.
resultsIn the intervention group, 4-6 months after the intervention, there was a significant decrease in the proportion of prescriptions containing an antibiotic from 15.2 ± 5.4% to 12.3 ± 5.8% (-2.8% [95% CI = -3.8 to -1.9], P<0.001). By contrast, an increase was observed in controls from 15.3 ± 6.0 to 16.4 ± 6.7% (+1.1% [95% CI = +0.4 to +1.8], P<0.01), resulting in a between-group difference of 3.93% ([95% CI = 2.75 to 5.11], P<0.001). The between-group difference was maintained 30 months after intervention (1.99% [95% CI = 0.56 to 3.42], P<0.01). Persistence of the intervention effect over the entire study period was confirmed in a hierarchical multivariate analysis.
conclusionThis randomised trial shows that a standardised and interactive educational seminar results in a long-term reduction in antibiotic prescribing and could justify a large-scale implementation of this intervention.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.