ArticleBMC microbiology2013
Isolation and characterization of diverse antimicrobial lipopeptides produced by Citrobacter and Enterobacter.
Article in BMC microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Biocontrol potentiality and plant growth-promoting traits of endophytic Enterobacter cloacae RO2 isolated from Portulaca oleracea L. against Bipolaris sorokiniana.Scientific reports · 2026Article
- Structural Characterization and Multiomics Analysis Reveal Extensive Diversity and Global Distribution of Kurstakin Lipopeptides.Journal of natural products · 2025Article
- EndophyticPlants (Basel, Switzerland) · 2025Article
- In Vitro and In Ovo Toxicity Analysis of Lipopeptides Biosurfactants Produced by Bacillus velezensis Strain AF_3B.Veterinary medicine and science · 2025Article
- Enhancement of low-density polyethylene biodegradation through the production of surface-active compounds by Pluralibacter gergoviae TYB1.Scientific reports · 2025Article
- Isolation and Identification of Endophytic Bacterium B5 fromJournal of fungi (Basel, Switzerland) · 2025Article
- Biocontrol of Phytophthora Root and Stem Rot and Growth Promotion of Soybean Plants by the Rhizobacterium Enterobacter pseudoroggenkampii Strain GVv1 Isolated from Vicia villosa Roth.Microbes and environments · 2025Article
- An Exceptionally Active and Highly Selective Perchlorate Transporter Containing a Trimesic Amide Scaffold.Molecules (Basel, Switzerland) · 2024Article
- Iturin: A Promising Cyclic Lipopeptide with Diverse Applications.Biomolecules · 2023Review
- Wild microbiomes of striped plateau lizards vary with reproductive season, sex, and body size.Scientific reports · 2022Article
- Microbial Antagonism in Food-Enrichment Culture: Inhibition of Shiga Toxin-ProducingFrontiers in microbiology · 2022Article
- Screening and Molecular Identification of Bacteria from the Midgut ofInternational journal of molecular sciences · 2021Article
- Microbial Lipopeptide-Producing Strains and Their Metabolic Roles under Anaerobic Conditions.Microorganisms · 2021Review
- Gut Bacteria ofACS omega · 2021Article
- Purification and identification of a surfactin biosurfactant and engine oil degradation by Bacillus velezensis KLP2016.Microbial cell factories · 2021Article
- LPD-12: a promising lipopeptide to control COVID-19.International journal of antimicrobial agents · 2021Article
- Bacteria from the Midgut of Common Cockchafer (International journal of molecular sciences · 2020Article
- Antibacterial and Anticancer Activity and Untargeted Secondary Metabolite Profiling of Crude Bacterial Endophyte Extracts fromInternational journal of microbiology · 2020Article
- Surfactin Like Broad Spectrum Antimicrobial Lipopeptide Co-produced With Sublancin FromFrontiers in microbiology · 2020Article
- Curd-Peptide Based Novel Hydrogel Inhibits Biofilm Formation, Quorum Sensing, Swimming Mortility of Multi-Antibiotic Resistant Clinical Isolates and Accelerates Wound Healing Activity.Frontiers in microbiology · 2019Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing multidrug-resistance in bacteria resulted in a greater need to find alternative antimicrobial substances that can be used for clinical applications or preservation of food and dairy products. Research on antimicrobial peptides including lipopeptides exhibiting both narrow and broad spectrum inhibition activities is increasing in the recent past. Therefore, the present study was aimed at isolation and characterization of antimicrobial lipopeptide producing bacterial strains from fecal contaminated soil sample.
resultsThe phenotypic and 16S rRNA gene sequence analysis of all isolates identified them as different species of Gram-negative genera Citrobacter and Enterobacter. They exhibited common phenotypic traits like citrate utilization, oxidase negative and facultative anaerobic growth. The HPLC analysis of solvent extracts obtained from cell free fermented broth revealed the presence of multiple antimicrobial lipopeptides. The comprehensive mass spectral analysis (MALDI-TOF MS and GC-MS) of HPLC purified fractions of different isolates revealed that the lipopeptides varied in their molecular weight between (m/z) 607.21 to 1536.16 Da. Isomers of mass ion m/z 984/985 Da was produced by all strains. The 1495 Da lipopeptides produced by strains S-3 and S-11 were fengycin analogues and most active against all strains. While amino acid analysis of lipopeptides suggested most of them had similar composition as in iturins, fengycins, kurstakins and surfactins, differences in their β-hydroxy fatty acid content proposed them to be isoforms of these lipopeptides.
conclusionAlthough antimicrobial producing strains can be used as biocontrol agents in food preservation, strains with ability to produce multiple antimicrobial lipopeptides have potential applications in biotechnology sectors such as pharmaceutical and cosmetic industry. This is the first report on antibacterial lipopeptides production by strains of Citrobacter and Enterobacter.
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