ArticleExperimental and clinical psychopharmacology2013
Sex differences in negative affect and lapse behavior during acute tobacco abstinence: a laboratory study.
Article in Experimental and clinical psychopharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Sex Differences in Tobacco Use Among Persons Living With HIV/AIDS: A Systematic Review and Meta-Analysis.Journal of acquired immune deficiency syndromes (1999) · 2017Pooled it
- Systematic and meta-analytic review of research examining the impact of menstrual cycle phase and ovarian hormones on smoking and cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015Pooled it
- Consideration of sex in clinical trials of transdermal nicotine patch: a systematic review.Experimental and clinical psychopharmacology · 2014Pooled it
- Exploring Gender Differences in Receipt of the 5As for Smoking Cessation for Recently Diagnosed Cancer Patients (ECOG-ACRIN EAQ171CD).Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- Pain characteristics and nicotine deprivation as predictors of performance during a laboratory paradigm of smoking cessation.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020Trial
- Ovarian Hormones and Transdermal Nicotine Administration Independently and Synergistically Suppress Tobacco Withdrawal Symptoms and Smoking Reinstatement in the Human Laboratory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Trial
- Second Generation Electronic Nicotine Delivery System Vape Pen Exposure Generalizes as a Smoking Cue.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018Trial
- Expectancies for the effectiveness of different tobacco interventions account for racial and gender differences in motivation to quit and abstinence self-efficacy.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2014Trial
- Understanding fatigue severity and smoking deprivation in smoking behavior and urges: A pilot test.Experimental and clinical psychopharmacology · 2025Article
- Attentional bias in tobacco use disorder using eye tracking: A systematic review.Drug and alcohol dependence reports · 2024Review
- Sex differences in contextual fear conditioning and extinction after acute and chronic nicotine treatment.Biology of sex differences · 2024Article
- The Role of Microglia in Sex- and Region-Specific Blood-Brain Barrier Integrity During Nicotine Withdrawal.Biological psychiatry global open science · 2024Article
- Sex Differences in the Association of E-cigarette and Cigarette Use and Dual Use With Self-Reported Hypertension Incidence in US Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Article
- Nicotine but not saline self-administering or yoked control conditions produces sustained neuroadaptations in the accumbens shell.Frontiers in molecular neuroscience · 2023Article
- The association between hormonal contraceptive use and smoking, negative affect, and cessation attempts in college females.Drug and alcohol dependence reports · 2022Article
- Affect and subjective cognitive functioning by depression symptom levels during naturalistic cigarette smoking in premenopausal females who smoke daily.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022Article
- Drug and alcohol dependence acute effects of pod-style e-cigarettes in vaping-naïve smokers.Drug and alcohol dependence · 2021Article
- Anhedonia in tobacco withdrawal among African-American smokers.Experimental and clinical psychopharmacology · 2021Article
- Rodent models for nicotine withdrawal.Journal of psychopharmacology (Oxford, England) · 2021Review
- Electronic nicotine delivery systems (ENDS) cue reactivity in dual users: A combined analysis.Drug and alcohol dependence · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Heightened negative affect during acute tobacco abstinence in women relative to men could be an important factor underlying sex differences in smoking motivation. However, little controlled experimental work addresses this hypothesis. The current study investigated sex differences in withdrawal-related negative affect, time to start smoking on a lab analogue smoking lapse task, and the interrelation between sex, withdrawal-related negative affect, and smoking lapse behavior. Following a baseline session, current smokers (women: n = 68, men: n = 131) attended two counterbalanced lab sessions (16 hours smoking abstinence and ad libitum smoking) during which they completed self-report measures of mood and withdrawal symptoms followed by a laboratory analogue smoking lapse task. In this task participants are monetarily rewarded for delaying smoking. Performance on this task serves as an analogue model of smoking lapse behavior by measuring smoker's capability to resist temptation to smoke under conditions where abstinence is advantageous. Females showed greater abstinence induced increases in composite negative affect as well as several particular negative affect states (i.e., POMS Anger, Anxiety, Depression, and Confusion, ps < .05) but no differences in abstinence induced changes in other forms of affect or craving. Females also exhibited marginally greater abstinence induced decreases in their willingness to delay smoking for money (p = .10), which was mediated by abstinence induced increases in anger (p < .05). These results suggest that differential sensitivity to abstinence induced negative affect, particularly anger, could underlie sex specific smoking patterns. Negative affect during tobacco abstinence may be an important factor for understanding and treating nicotine addiction in women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.