Evidence map›Paper›PMID 23834220›Full record

ReviewASN neuro2013

Node of Ranvier disruption as a cause of neurological diseases.

Keiichiro Susuki

Abstract readReview
In one paragraph

Review in ASN neuro, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Cytoskeletal scaffolding of NaCurrent opinion in cell biology · 2025
    Review
  6. Article
  7. Metabolic implications of axonal demyelination and its consequences for synchronized network activity: AnJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  8. Review
  9. Application of SygenBioengineering (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Noise-Induced Dysregulation ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Keiichiro SusukiDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA. susuki@bcm.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysfunction and/or disruption of nodes of Ranvier are now recognized as key contributors to the pathophysiology of various neurological diseases. One reason is that the excitable nodal axolemma contains a high density of Nav (voltage-gated Na+ channels) that are required for the rapid and efficient saltatory conduction of action potentials. Nodal physiology is disturbed by altered function, localization, and expression of voltage-gated ion channels clustered at nodes and juxtaparanodes, and by disrupted axon-glial interactions at paranodes. This paper reviews recent discoveries in molecular/cellular neuroscience, genetics, immunology, and neurology that highlight the critical roles of nodes of Ranvier in health and disease.

Indexed as

AnimalsAutoimmune Diseases of the Nervous SystemCentral Nervous SystemChannelopathiesDemyelinating DiseasesHumansIon ChannelsNerve Tissue ProteinsNervous System DiseasesPeripheral Nervous SystemRanvier's NodesIon ChannelsNerve Tissue Proteins

Identifiers

PMID23834220
PMCPMC3736360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.