ArticleVeterinary research2013
The non-pathogenic Australian rabbit calicivirus RCV-A1 provides temporal and partial cross protection to lethal Rabbit Haemorrhagic Disease Virus infection which is not dependent on antibody titres.
Article in Veterinary research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Characterisation ofInternational journal of molecular sciences · 2024Review
- First Detection of Benign Rabbit Caliciviruses in Chile.Viruses · 2024Article
- Article
- Sustained Impact of RHDV2 on Wild Rabbit Populations across Australia Eight Years after Its Initial Detection.Viruses · 2023Article
- Comparative Epidemiology of Rabbit Haemorrhagic Disease Virus Strains from Viral Sequence Data.Viruses · 2022Article
- Article
- Passive Immunisation against RHDV2 Induces Protection against Disease but Not Infection.Vaccines · 2021Article
- A Review on the Methods Used for the Detection and Diagnosis of Rabbit Hemorrhagic Disease Virus (RHDV).Microorganisms · 2021Review
- Immunity againstVaccines · 2021Review
- Culture and differentiation of rabbit intestinal organoids and organoid-derived cell monolayers.Scientific reports · 2021Article
- The impact of RHDV-K5 on rabbit populations in Australia: an evaluation of citizen science surveys to monitor rabbit abundance.Scientific reports · 2019Article
- The discovery of three new hare lagoviruses reveals unexplored viral diversity in this genus.Virus evolution · 2019Article
- Elucidation of the pathology and tissue distribution of Lagovirus europaeus GI.2/RHDV2 (rabbit haemorrhagic disease virus 2) in young and adult rabbits (Oryctolagus cuniculus).Veterinary research · 2018Article
- Article
- Benign Rabbit Calicivirus in New Zealand.Applied and environmental microbiology · 2017Article
- Benign Rabbit Caliciviruses Exhibit Evolutionary Dynamics Similar to Those of Their Virulent Relatives.Journal of virology · 2016Article
- Comparative Phylodynamics of Rabbit Hemorrhagic Disease Virus in Australia and New Zealand.Journal of virology · 2015Article
- Timing and severity of immunizing diseases in rabbits is controlled by seasonal matching of host and pathogen dynamics.Journal of the Royal Society, Interface · 2015Article
- Viral biocontrol: grand experiments in disease emergence and evolution.Trends in microbiology · 2015Review
- Rabbit haemorrhagic disease: virus persistence and adaptation in Australia.Evolutionary applications · 2014Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endemic non-pathogenic Australian rabbit calicivirus RCV-A1 is known to provide some cross protection to lethal infection with the closely related Rabbit Haemorrhagic Disease Virus (RHDV). Despite its obvious negative impacts on viral biocontrol of introduced European rabbits in Australia, little is known about the extent and mechanisms of this cross protection. In this study 46 rabbits from a colony naturally infected with RCV-A1 were exposed to RHDV. Survival rates and survival times did not correlate with titres of serum antibodies specific to RCV-A1 or cross reacting to RHDV, but were instead influenced by the time between infection with the two viruses, demonstrating for the first time that the cross protection to lethal RHDV infection is transient. These findings are an important step towards a better understanding of the complex interactions of co-occurring pathogenic and non-pathogenic lagoviruses.
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