Evidence map›Paper›PMID 23834187›Full record

ReviewCurrent medicinal chemistry2013

Nanocarriers for tracking and treating diseases.

Sean Marrache, Rakesh Kumar Pathak, Kasey L Darley, Joshua H Choi, Dhillon Zaver, Nagesh Kolishetti, Shanta Dhar

Abstract readReview
In one paragraph

Review in Current medicinal chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
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  7. Article
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  10. Multifunctional quantum dot DNA hydrogels.Nature communications · 2017
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Drug delivery to the ischemic brain.Advances in pharmacology (San Diego, Calif.) · 2014
    Review
  19. Targeted nanoparticles in mitochondrial medicine.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean MarracheNanoTherapeutics Research Laboratory, Department of Chemistry, University of Georgia, Athens, GA 30602, USA.
Rakesh Kumar Pathak
Kasey L Darley
Joshua H Choi
Dhillon Zaver
Nagesh Kolishetti
Shanta Dhar

Funding

Recruitment of a Bioinorganic Chemistry Faculty MemberP30GM092378 · NIGMS · UNIVERSITY OF GEORGIA · PI JOHNSON, MICHAEL K. · 2009 to 2010
$684k
NIGMS NIH HHS P30 GM092378NIGMS NIH HHS P30GM092378
6 · The paper itself

Abstract

Site directed drug delivery with high efficacy is the biggest challenge in the area of current pharmaceuticals. Biodegradable polymer-based controlled release nanoparticle platforms could be beneficial for targeted delivery of therapeutics and contrast agents for a myriad of important human diseases. Biodegradable nanoparticles, which can be engineered to load multiple drugs with varied physicochemical properties, contrast agents, and cellular or intracellular component targeting moieties, have emerged as potential alternatives for tracking and treating human diseases. In this review, we will highlight the current advances in the design and execution of such platforms for their potential application in the diagnosis and treatment of variety of diseases ranging from cancer to Alzheimer's and we will provide a critical analysis of the associated challenges for their possible clinical translation.

Indexed as

Antineoplastic AgentsBiocompatible MaterialsBlood-Brain BarrierCardiovascular DiseasesContrast MediaDrug CarriersHumansNanoparticlesNeoplasmsNeurodegenerative DiseasesPolymersAntineoplastic AgentsBiocompatible MaterialsContrast MediaDrug CarriersPolymers

Identifiers

PMID23834187
PMCPMC8085808

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.