Evidence map›Paper›PMID 23833288›Full record

ArticleCirculation research2013

Killing two birds with one stone, maybe: CETP inhibition increases both high-density lipoprotein levels and insulin secretion.

Sergio Fazio, MacRae F Linton

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. HDL Cholesterol and Non-Cardiovascular Disease: A Narrative Review.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sergio Fazio
MacRae F Linton

Funding

FUNCTIONAL HIERARCHY OF REMNANT LIPOPROTEIN RECEPTORSR01HL057986 · NHLBI · VANDERBILT UNIVERSITY · PI FAZIO, SERGIO · 1998 to 2016
$6.2M
PCSK9, Lipoprotein receptors, and AtherosclerosisR01HL106845 · NHLBI · VANDERBILT UNIVERSITY · PI FAZIO, SERGIO · 2011 to 2014
$2.0M
Macrophage Akt and IKKalpha signaling in apoptosis and atherosclerosisR01HL105375 · NHLBI · VANDERBILT UNIVERSITY · PI LINTON, MACRAE F · 2010 to 2013
$1.8M
Mechanisms for Dysfunctional HDL Formation in Familial HypercholesterolemiaR01HL111945 · NHLBI · VANDERBILT UNIVERSITY · PI LINTON, MACRAE F · 2012 to 2013
$920k
NHLBI NIH HHS HL105375NHLBI NIH HHS HL106845NHLBI NIH HHS HL111945NHLBI NIH HHS HL57986NHLBI NIH HHS R01 HL057986NHLBI NIH HHS R01 HL105375NHLBI NIH HHS R01 HL106845NHLBI NIH HHS R01 HL111945
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCholesterol Ester Transfer ProteinsCholesterol, HDLHumansInsulinInsulin SecretionMaleCETP protein, humanCholesterol Ester Transfer ProteinsCholesterol, HDLInsulinbeta cellCETP inhibitorsEditorialsHDLinsulin

Identifiers

PMID23833288
PMCPMC3953452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.