ArticleThe British journal of radiology2013
Effects of a difference in respiratory cycle between treatment planning and irradiation for phase-controlled rescanning and carbon pencil beam scanning.
Article in The British journal of radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Comparative evaluation of static and dynamic 4D dose recalculations in pencil beam scanning proton therapy for oesophageal cancer.Physics and imaging in radiation oncology · 2026Article
- Article
- Safety and Efficacy of Single-Fraction Carbon-Ion Radiotherapy for Early-Stage Lung Cancer with Interstitial Pneumonia.Cancers · 2024Article
- A survey of practice patterns for real-time intrafractional motion-management in particle therapy.Physics and imaging in radiation oncology · 2023Article
- Beam properties within the momentum acceptance of a clinical gantry beamline for proton therapy.Medical physics · 2022Article
- Commissioning of carbon-ion radiotherapy for moving targets at the Osaka Heavy-Ion Therapy Center.Medical physics · 2022Article
- A new emittance selection system to maximize beam transmission for low-energy beams in cyclotron-based proton therapy facilities with gantry.Medical physics · 2021Article
- Commissioning of a respiratory gating system involving a pressure sensor in carbon-ion scanning radiotherapy.Journal of applied clinical medical physics · 2019Article
- Intrafractional dose variation and beam configuration in carbon ion radiotherapy for esophageal cancer.Radiation oncology (London, England) · 2016Article
- Particle therapy of moving targets-the strategies for tumour motion monitoring and moving targets irradiation.The British journal of radiology · 2016Review
- Reducing Dose Uncertainty for Spot-Scanning Proton Beam Therapy of Moving Tumors by Optimizing the Spot Delivery Sequence.International journal of radiation oncology, biology, physics · 2015Article
- Effect of secondary particles on image quality of dynamic flat panels in carbon ion scanning beam treatment.The British journal of radiology · 2015Article
- Implementation of a target volume design function for intrafractional range variation in a particle beam treatment planning system.The British journal of radiology · 2014Article
- Carbon ion therapy for early-stage non-small-cell lung cancer.BioMed research international · 2014Review
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Authors and funding
6 authors.
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Abstract
objectiveTo evaluate the impact of variation in respiratory cycle between treatment planning and irradiation for pencil beam scanning and phase-controlled rescanning (PCR) on the resulting dose distribution, we conducted a simulation study based on four-dimensional CT (4DCT) data for lung cancer patients.
methods4DCT data were acquired for seven patients with lung tumours. Treatment planning was designed to ensure the delivery of 95% of the prescribed dose to the clinical target volume in respective phases of the 4DCT by taking account of intrafractional beam range variations. Carbon ion pencil beam scanning dose distributions were calculated for various respiratory cycles that differed from the reference respiration (=4.4 s) but which stayed regular during irradiation. The number of rescannings was changed to 1, 4 or 8 times. PCR was correlated with the gating window in treatment planning to calculate the beam weighting map.
results8×PCR improved dose conformation to the target for all irradiation respiratory cycles. Minimum dose (Dmin) and lowest dose encompassing 95% of the target (D95) values with 4×PCR were decreased from 94.1% and 98.1% to 88.4% and 93.5% with an altered irradiation respiratory cycle of 2.4 s. However, these values were improved with 8×PCR to over 94.9% for Dmin and 98.6% for D95 for respective irradiation respiratory cycles.
conclusionPencil beam scanning treatment with eight or more PCRs consistently improved dose conformation for moving lung targets even when different respiratory cycles were used for treatment planning and irradiation. ADVANCES IN KNOWLEDGE: Scanning treatment with eight or more rescannings consistently improved dose homogeneity to a moving target even though respiratory cycles varied during treatment.
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