ArticleMacromolecular bioscience2013
Collagen-polymer guidance of vessel network formation and stabilization by endothelial colony forming cells in vitro.
Article in Macromolecular bioscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 37 citations in OpenAlex.
- Immunotolerant Oligomer scaffolds promote regenerative remodeling and improved muscle structure and function after volumetric muscle loss.Scientific reports · 2026Article
- Association of collagen deep learning classifier with prognosis and chemotherapy benefits in stage II-III colon cancer.Bioengineering & translational medicine · 2023Article
- VEGF-Encoding, Gene-Activated Collagen-Based Matrices Promote Blood Vessel Formation and Improved Wound Repair.ACS applied materials & interfaces · 2023Article
- Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair.Nature communications · 2023Article
- The relationship between cancer and biomechanics.Frontiers in oncology · 2023Review
- Article
- Regenerative tissue filler for breast conserving surgery and other soft tissue restoration and reconstruction needs.Scientific reports · 2021Article
- Hydrogels and Dentin-Pulp Complex Regeneration: From the Benchtop to Clinical Translation.Polymers · 2020Review
- Assessment of progressive alterations in collagen organization in the postoperative conjunctiva by multiphoton microscopy.Biomedical optics express · 2020Article
- Oligomeric collagen as an encapsulation material for islet/β-cell replacement: effect of islet source, dose, implant site, and administration format.American journal of physiology. Endocrinology and metabolism · 2020Article
- Injectable Highly Tunable Oligomeric Collagen Matrices for Dental Tissue Regeneration.ACS applied bio materials · 2020Article
- Design and biofabrication of dermal regeneration scaffolds: role of oligomeric collagen fibril density and architecture.Regenerative medicine · 2020Article
- The role of collagen in cancer: from bench to bedside.Journal of translational medicine · 2019Review
- YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility.The Journal of cell biology · 2019Article
- In situ type I oligomeric collagen macroencapsulation promotes islet longevity and function in vitro and in vivo.American journal of physiology. Endocrinology and metabolism · 2018Article
- Three-dimensional tissue-engineered skeletal muscle for laryngeal reconstruction.The Laryngoscope · 2018Article
- Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition.PloS one · 2018Article
- Murine ultrasound-guided transabdominal para-aortic injections of self-assembling type I collagen oligomers.Journal of controlled release : official journal of the Controlled Release Society · 2017Article
- Matrix stiffening promotes a tumor vasculature phenotype.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Vessel morphogenesis is vital to regenerative medicine strategies. Here, collagen polymers, specified by intermolecular cross-link composition, are used to independently vary microstructure (fibril density, interfibril branching) and physical properties (stiffness) to guide 3D vessel network formation by endothelial colony forming cells (ECFC) in vitro. Increasing stiffness, by modulation of fibril density or interfibril branching, increases vessel diameter, length and branching. Oligomer matrices also induce vessel stabilization via type IV collagen deposition. This work shows that ECFC vessel formation depends on the interplay of collagen microstructure and physical properties and names oligomers and intermolecular cross-links as key design parameters for vascular-inductive matrices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.