Evidence map›Paper›PMID 23832339›Full record

ReviewBioscience, biotechnology, and biochemistry2013

Gustatory neural pathways revealed by genetic tracing from taste receptor cells.

Ichiro Matsumoto

Open access · bronzeAbstract readReview
In one paragraph

Review in Bioscience, biotechnology, and biochemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. International society of sports nutrition position stand: caffeine and exercise performance.Journal of the International Society of Sports Nutrition · 2021
    Review
  5. Article
  6. Administration of Caffeine in Alternate Forms.Sports medicine (Auckland, N.Z.) · 2018
    Review
  7. Bitters: Time for a New Paradigm.Evidence-based complementary and alternative medicine : eCAM · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ichiro MatsumotoMonell Chemical Senses Center, Philadelphia, PA 19104, USA. imatsumoto@monell.org
Monell Chemical Senses Center · US

Funding

New Genetic Tracers for Concurrent Labeling of Multiple Gustatory Neural PathwaysR03DC011143 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI MATSUMOTO, ICHIRO · 2010 to 2012
$432k
NIDCD NIH HHS DC011143NIDCD NIH HHS R03 DC011143
6 · The paper itself

Abstract

Taste receptor cells encounter chemicals in foods and transmit this information to the gustatory neurons, which convey it further to the gustatory relay nuclei in the lower brainstem. Characterizing neurons involved in the transmission of gustatory information in the peripheral and central nervous systems helps us better understand how we perceive and discriminate tastes. However, it is difficult to anatomically identify them. Using cell-type-specific promoters/enhancers and a transneuronal tracer, we generated transgenic mice to visualize neurons in the gustatory neural pathways. We observed the tracer in the neurons of cranial sensory ganglia and the nucleus of the solitary tract in the medulla where gustatory neurons project. The tracer was also distributed in the reticular formation and several motor nuclei in the medulla that have not been recognized as gustatory ascending pathways. These transgenic mice revealed gustatory relay neurons in the known gustatory ascending pathway and an unexpected, thus presumably novel, neural circuit of gustatory system.

Indexed as

Nervous System Physiological PhenomenaTaste PerceptionAnimalsBrain StemHumansMolecular BiologyNeuronsWheat Germ AgglutininsWheat Germ Agglutinins

Identifiers

PMID23832339
PMCPMC3804333
OpenAlexW2033411256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.