ArticleEuropean radiology2013
3-T MRI with diffusion tensor imaging and tractography of the median nerve.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Can Diffusion Tensor Imaging Apparent Diffusion Coefficient Diagnose Carpal Tunnel Syndrome? A Systematic Review and Meta-Analysis.Hand (New York, N.Y.) · 2023Pooled it
- Utility of MRI Diffusion Tensor Imaging in Carpal Tunnel Syndrome: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2016Pooled it
- Three-Dimensional Magnetic Resonance Imaging of Median Nerve Volume for Assessing Carpal Tunnel Syndrome Severity.Muscle & nerve · 2025Article
- Article
- Advances in Imaging of Compressive Neuropathies.Hand clinics · 2024Review
- Assessment of median nerve with magnetic resonance neurography in cases with carpal tunnel syndrome and controls.Current journal of neurology · 2024Article
- Future Considerations in the Diagnosis and Treatment of Compressive Neuropathies of the Upper Extremity.Journal of hand surgery global online · 2023Review
- Correlation between diffusion tensor indices and fascicular morphometric parameters of peripheral nerve.Frontiers in physiology · 2023Article
- Deep CTS: a Deep Neural Network for Identification MRI of Carpal Tunnel Syndrome.Journal of digital imaging · 2022Article
- New insights into the evaluation of peripheral nerves lesions: a survival guide for beginners.Neuroradiology · 2022Review
- Visualization of the morphological changes in the median nerve after carpal tunnel release using three-dimensional magnetic resonance imaging.European radiology · 2022Article
- Evaluation of Brachial Plexus Using Combined Stereological Techniques of Diffusion Tensor Imaging and Fiber Tracking.Journal of brachial plexus and peripheral nerve injury · 2019Article
- The efficiency of acoustic radiation force impulse (ARFI) elastography in the diagnosis and staging of carpal tunnel syndrome.Journal of medical ultrasonics (2001) · 2018Article
- Carpal tunnel syndrome assessment with diffusion tensor imaging: Value of fractional anisotropy and apparent diffusion coefficient.European radiology · 2018Article
- The Median Nerve at the Carpal Tunnel … and Elsewhere.Journal of the Belgian Society of Radiology · 2018Article
- Quantitative magnetic resonance (MR) neurography for evaluation of peripheral nerves and plexus injuries.Quantitative imaging in medicine and surgery · 2017Review
- MRI shows thickening and altered diffusion in the median and ulnar nerves in multifocal motor neuropathy.European radiology · 2017Article
- Parotid gland tumours: MR tractography to assess contact with the facial nerve.European radiology · 2016Article
- Accelerated magnetic resonance diffusion tensor imaging of the median nerve using simultaneous multi-slice echo planar imaging with blipped CAIPIRINHA.European radiology · 2016Article
- Fascicular Topography of the Human Median Nerve for Neuroprosthetic Surgery.Frontiers in neuroscience · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo apply diffusion tensor imaging (DTI) and tractography to the median nerve by use of a 3-T MRI device in order to demonstrate potential differences in diffusion parameters between healthy subjects and patients with carpal tunnel syndrome (CTS).
methodsThe median nerve of 15 patients and 20 healthy volunteers was examined in two sequences: DTI and a high-resolution T1-weighted sequence. Mean fractional anisotropy (FA) and mean apparent diffusion coefficient (ADC) were measured based on tractography findings. Mean FA was significantly lower in CTS patients (P = 0.01) whereas no significant difference was found in mean ADC. Focal measurements of FA and ADC were also obtained at three locations along the course of the median nerve.
resultsWe observed a highly significant difference (P < 0.0001) between FA measured at the proximal carpus and FA measured at the distal carpus in healthy subjects and CTS patients. Focal FA values along the median nerve showed an opposite trend in the two groups: in healthy subjects FA tended to increase (P < 0.05) whereas in subjects with CTS it tended to decrease (P = 0.0001). We defined a threshold value of -0.058 (FA3-FA1) that was sensitive and specific for nerve compression.
conclusionDTI and tractography can detect chronic nerve compression. KEY POINTS: • Diffusion tensor magnetic resonance imaging offers new information about carpal tunnel syndrome. • Diffusion tensor MRI of the median nerve provides some functional data. • Mean fractional anisotropy (FA) was lower in patients with CTS than volunteers. • There was no significant difference in ADC values between patients and volunteers. • Fractional anisotropy seems a sensitive and specific predictor of chronic nerve compression.
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