ReviewExperimental gerontology2013
Obesity and diabetes as accelerators of functional decline: can lifestyle interventions maintain functional status in high risk older adults?
Review in Experimental gerontology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dose Response of Eccentric Exercises on Glycemic Control in Type ii Diabetes Mellitus
Fasting to Provide Energy Needed to Help Adults in Need of Cognitive Enhancement (FASTING ENHANCE)
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The impact of time-restricted eating on health-related quality of life: a systematic literature review.Nutrition reviews · 2025Pooled it
- Association of body mass index with disability in activities of daily living in older adults: a systematic review of the literature based on longitudinal data.BMC public health · 2025Pooled it
- How can clinical practices pragmatically increase physical activity for patients with type 2 diabetes? A systematic review.Translational behavioral medicine · 2017Pooled it
- The Effects of Online Home-Based Pilates Combined with Diet on Body Composition in Women Affected by Obesity: A Preliminary Study.Nutrients · 2024Trial
- Acute application of photobiomodulation does not bring important gains for the muscular performance and functionality of diabetic individuals.Lasers in medical science · 2021Trial
- Novel Smartphone Game Improves Physical Activity Behavior in Type 2 Diabetes.American journal of preventive medicine · 2019Trial
- Trial
- Effects of resistance training with and without caloric restriction on physical function and mobility in overweight and obese older adults: a randomized controlled trial.The American journal of clinical nutrition · 2015Trial
- Healthy behavior change and cardiovascular outcomes in newly diagnosed type 2 diabetic patients: a cohort analysis of the ADDITION-Cambridge study.Diabetes care · 2014Trial
- Article
- EXERCISE BENEFITS AND BARRIERS IN AN EXTENSION-DELIVERED DIABETES PREVENTION PROGRAM.Family and consumer sciences research journal · 2025Article
- The DASH diet in diabetes related complications or comorbidities: an unexpected friend.Frontiers in nutrition · 2025Review
- Serum vitamin D concentration and anthropometric indicators of adiposity in adults without or with low dose statin users: a cross-sectional study.Journal of health, population, and nutrition · 2024Article
- Time-restricted eating: Watching the clock to treat obesity.Cell metabolism · 2024Review
- Chronic Resistance Training Effects on Serum Adipokines in Type 2 Diabetes Mellitus: A Systematic Review.Healthcare (Basel, Switzerland) · 2023Review
- Obesity in early adulthood and physical functioning in mid-life: Investigating the mediating role of c-reactive protein.Brain, behavior, and immunity · 2022Article
- Potential Mechanisms for How Long-Term Physical Activity May Reduce Insulin Resistance.Metabolites · 2022Review
- Effects of lifestyle interventions on rural patients with type 2 diabetes mellitus.World journal of diabetes · 2020Article
- Exploring the Impact of Obesity on Skeletal Muscle Function in Older Age.Frontiers in nutrition · 2020Review
- Type 2 Diabetes Correlates with Comorbidity and Nutritional Status but Not with Functional Health in Geriatric Ward Patients: A Cross-Sectional Study in Poland.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Obesity and diabetes are known risk factors for the development of physical disability among older adults. With the number of seniors with these conditions rising worldwide, the prevention and treatment of physical disability in these persons have become a major public health challenge. Sarcopenia, the progressive loss of muscle mass and strength, has been identified as a common pathway associated with the initial onset and progression of physical disability among older adults. A growing body of evidence suggests that metabolic dysregulation associated with obesity and diabetes accelerates the progression of sarcopenia, and subsequently functional decline in older adults. The focus of this brief review is on the contributions of obesity and diabetes in accelerating sarcopenia and functional decline among older adults. We also briefly discuss the underexplored interaction between obesity and diabetes that may further accelerate sarcopenia and place obese older adults with diabetes at particularly high risk of disability. Finally, we review findings from studies that have specifically tested the efficacy of lifestyle-based interventions in maintaining the functional status of older persons with obesity and/or diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.