ArticleEpidemiology and infection2014
Optimal design of studies of influenza transmission in households. II: comparison between cohort and case-ascertained studies.
Article in Epidemiology and infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Estimating influenza transmission parameters: Comparing two study designs, 2023-2024.Epidemics · 2026Article
- Estimated Effectiveness of Influenza Vaccines in Preventing Secondary Infections in Households.JAMA network open · 2024Article
- The role of asymptomatic infections in influenza transmission: what do we really know.The Lancet. Infectious diseases · 2024Review
- Retrospective, Observational Studies for Estimating Vaccine Effects on the Secondary Attack Rate of SARS-CoV-2.American journal of epidemiology · 2023Observational
- Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities-workshop report.NPJ vaccines · 2023Article
- Home collection of nasal swabs for detection of influenza in the Household Influenza Vaccine Evaluation Study.Influenza and other respiratory viruses · 2021Article
- SARS-CoV-2 Transmissibility Within Day Care Centers-Study Protocol of a Prospective Analysis of Outbreaks in Germany.Frontiers in public health · 2021Article
- Transmission of respiratory and gastrointestinal infections in German households with children attending child care.Epidemiology and infection · 2018Article
- Scabies in residential care homes: Modelling, inference and interventions for well-connected population sub-units.PLoS computational biology · 2018Article
- Application of an Individual-Based Transmission Hazard Model for Estimation of Influenza Vaccine Effectiveness in a Household Cohort.American journal of epidemiology · 2017Article
- Algorithms for detecting and predicting influenza outbreaks: metanarrative review of prospective evaluations.BMJ open · 2016Article
- Household Transmission of Influenza Virus.Trends in microbiology · 2016Review
- Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study.The Lancet. Respiratory medicine · 2014Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Both case-ascertained household studies, in which households are recruited after an 'index case' is identified, and household cohort studies, where a household is enrolled before the start of the epidemic, may be used to test and estimate the protective effect of interventions used to prevent influenza transmission. A simulation approach parameterized with empirical data from household studies was used to evaluate and compare the statistical power of four study designs: a cohort study with routine virological testing of household contacts of infected index case, a cohort study where only household contacts with acute respiratory illness (ARI) are sampled for virological testing, a case-ascertained study with routine virological testing of household contacts, and a case-ascertained study where only household contacts with ARI are sampled for virological testing. We found that a case-ascertained study with ARI-triggered testing would be the most powerful design while a cohort design only testing household contacts with ARI was the least powerful. Sensitivity analysis demonstrated that these conclusions varied by model parameters including the serial interval and the risk of influenza virus infection from outside the household.
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Registered trials
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