Evidence map›Paper›PMID 23830127›Full record

ReviewImmunology and allergy clinics of North America2013

Role of cells and mediators in exercise-induced bronchoconstriction.

Teal S Hallstrand, William A Altemeier, Moira L Aitken, William R Henderson

Open access · greenAbstract readReview
In one paragraph

Review in Immunology and allergy clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Asthma, atopy, and exercise: Sex differences in exercise-induced bronchoconstriction.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Teal S HallstrandDivision of Pulmonary and Critical Care, Department of Medicine, University of Washington, 1959 NE Pacific Street, Box 356522, Seattle, WA 98195-6522, USA. tealh@uw.edu
William A Altemeier
Moira L Aitken
William R Henderson
University of Washington · USUnion University · US

Funding

Secretory Phospholipase A2s in Airway PathophysiologyR01HL089215 · NHLBI · UNIVERSITY OF WASHINGTON · PI HALLSTRAND, TEAL S · 2008 to 2017
$4.0M
NHLBI NIH HHS HL089215NHLBI NIH HHS R01 HL089215
6 · The paper itself

Abstract

A susceptible group of subjects with asthma develops airflow obstruction in response to the transfer of water out of the airways during exercise. The transfer of water or the challenge with a hypertonic solution serves as a strong stimulus to the airway epithelium. Susceptible subjects have epithelial shedding into the airway lumen, and airway inflammation that leads to the overproduction of leukotrienes and other eicosanoids following exercise challenge. The sensory nerves of the airways may serve as a critical link that mediates the effect of eicosanoids, leading to bronchoconstriction and mucus production in response to exercise challenge.

Indexed as

Airway RemodelingAsthma, Exercise-InducedEicosanoidsHumansInflammation MediatorsLeukocytesRespiratory MucosaRespiratory SystemEicosanoidsInflammation MediatorsAsthmaEicosanoidEosinophilExercise-induced bronchoconstrictionLeukotrieneMast cellPhospholipaseProstaglandin

Identifiers

PMID23830127
PMCPMC3763828
OpenAlexW1976483832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.