ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Treatment outcome of tuberculosis patients under directly observed treatment in Addis Ababa, Ethiopia.
Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis.BMC infectious diseases · 2016Pooled it
- Time to recovery among tuberculosis patients receiving anti-Koch's drug in Ibadan, Oyo State, Nigeria.BMC infectious diseases · 2025Article
- Tuberculosis incidence and treatment outcomes in the Tarmaber District, Ethiopia: a five-year retrospective study.BMC infectious diseases · 2025Article
- Tuberculosis treatment outcomes and their determinants among patients attending Hargeisa TB Hospital: a five-year retrospective study.The Pan African medical journal · 2025Article
- The Treatment Outcomes of Tuberculosis Patients at Adare General Hospital, Southern Ethiopia (A Five-Year Retrospective Study).Tropical medicine and infectious disease · 2024Article
- Tuberculosis treatment outcomes and associated factors among tuberculosis patients treated at healthcare facilities of Motta Town, Northwest Ethiopia: a five-year retrospective study.Scientific reports · 2024Article
- Predictors of tuberculosis treatment outcome at Senkatana clinic in Lesotho.The Pan African medical journal · 2024Article
- Diagnosis and Management of Adult Tuberculosis Patients Admitted to a Rural Hospital in Ethiopia.Cureus · 2023Article
- High variability in tuberculosis treatment outcomes across 15 health facilities in a semi-urban area in central Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- Bedaquiline Resistance and Molecular Characterization of Rifampicin-ResistantInfection and drug resistance · 2023Article
- Determinants of Unsuccessful TB Treatment Outcomes Among Patients on Directly Observed Treatment Short Course in Jimma Town Health Facilities, Southwest Ethiopia: A Case-Control Study.Infection and drug resistance · 2023Article
- Article
- Tuberculosis Treatment Outcomes and Its Predictors among Tuberculosis Patients Registered at Tefera Hailu Memorial General Hospital, Sekota Town, Northeast Ethiopia: A Seven-Year Retrospective Study.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Article
- Trends of Tuberculosis Disease from 2013-2018 in Bale Zone, Oromia Region, Ethiopia. Retrospective Review.Infection and drug resistance · 2022Article
- Analysis of drug resistance among difficult-to-treat tuberculosis patients in Ghana identifies several pre-XDR TB cases.Frontiers in microbiology · 2022Article
- Article
- Trends and outcomes of tuberculosis among cases on directly observed short course treatment (DOTS) at Tepi public health center Southwest Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2021Article
- Impact of HIV-AIDS on tuberculosis treatment outcome in Southern Ethiopia - A retrospective cohort study.Journal of clinical tuberculosis and other mycobacterial diseases · 2021Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTuberculosis is one of the leading causes of mortality among infectious diseases worldwide. For effective tuberculosis control, it is a pre-requisite to detect the cases as early as possible, and to ensure that the tuberculosis patients complete their treatment and get cured. However, in many resource-constrained settings treatment outcome for tuberculosis has not been satisfactory.
objectiveThe aim of the study was to assess the treatment outcome of tuberculosis patients and investigate the association of demographic and clinical factors with treatment success of patients enrolled in Directly Observed Treatment Short Course program in government owned health centers over the course of five consecutive years in Addis Ababa, Ethiopia.
methodsA register based historical cohort study covering the period of July 2004 to June 2009 was conducted to determine the treatment outcome of Directly Observed Treatment Short Course in government owned health centers in Addis Ababa. Sex and age of tuberculosis patients, health center at which the patient was treated, year of treatment, type of tuberculosis for which the patient was treated, type of treatment offered to the patient, follow-up status and documented treatment outcome were extracted from the Directly Observed Treatment Short Course clinics of three randomly selected health centers.
resultRecords of 6450 registered tuberculosis patients (n=3147 males and 3433 females) were included in this document review. Of these patients 18.1% were reported as being cured, 64.6% were documented as treatment completed, 3.7% died during follow-up, 5.1% were reported as defaulters, 0.4% were documented as treatment failure and 8.2% were transferred out to another health institution. Treatment center and year of enrollment were significantly associated with treatment success.
conclusionYear of enrollment and treatment center were significantly associated with treatment success. Although the overall treatment success obtained in this study is in line with the World Health Organization (WHO) target, continuous follow-up of patients with frequent supportive supervision during the course of treatment, and further investigate the cause for the observed difference in treatment success across treatment centers are recommended.
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